QuickView for Mdm1 (gene)

Gene Symbol:

MDM1 Homo sapiens

Full name:

Mdm1 nuclear protein

Synonyms:

nuclear protein MDM1, Mdm4, transformed 3T3 cell double minute 1, p53 binding protein, nuclear protein double minute 1

Genomic Location:

Chr 12: 66974613-67012379

Description:

This gene encodes a microtubule-binding nuclear protein that localizes to the centrioles of dividing cells and differentiating multiciliated cells, and negatively regulates centriole duplication. The encoded protein is closely associated with the centriole barrel, and resides in the centriole lumen. naturally occurring mutations in the orthologous ...

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This gene encodes a microtubule-binding nuclear protein that localizes to the centrioles of dividing cells and differentiating multiciliated cells, and negatively regulates centriole duplication. The encoded protein is closely associated with the centriole barrel, and resides in the centriole lumen. naturally occurring mutations in the orthologous mouse gene are associated with age-related retinal degeneration.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ATGTCAC_MIR489 ,  TTTGTAG_MIR520D ,  CAGTGTT_MIR141_MIR200A ,  MYB_Q5_01 ,  AATGGAG_MIR136 ,  CAGGTG_E12_Q6 ,  GTTTGTT_MIR495 ,  GGGCGGR_SP1_Q6 ,  CTTTAAR_UNKNOWN ,  MYB_Q6 ,  POU3F2_02 ,  CTTTGT_LEF1_Q2 ,  BRN2_01 ,  USF_02

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-542-3p ,  Predicted Gene Targets for miR-455

Cytogenetic Map:

12q15

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