Name: | Metipranolol |
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PubChem Compound ID: | 31477 |
Description: | A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent. |
Molecular formula: | C17H27NO4 |
Molecular weight: | 309.401 g/mol |
Synonyms: |
C07915; Metipranolol; BRN 2152010; (+-)-1-(4-Hydroxy-2,3,5-trimethylphenoxy)-3-(isopropylamino)-2-propanol 4-acetate; 1-(4-Hydroxy-2,3,5-trimethylphenoxy)-3-(isopropylamino)-2-propanol 4-acetate; 38202-74-3; Metipranolol (USAN); Phenol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-2,3,6-trimethyl-, (+-)-, 1-acetate; VUFB-6453; 4-(2-Hydroxy-3-((1-methylethyl)-amino)propoxy)-2,3,6-trimethylphenol 1-acetate.
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Name: | Metipranolol |
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Name (isomeric): | DB01214 |
Drug Type: | small molecule |
Description: | A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent. |
Synonyms: |
Metipranolol hydrochloride; Metipranololum [INN-Latin]
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Brand: | Trimepranol, OptiPranolol, Disorat |
Category: | Sympatholytics, Adrenergic beta-Antagonists, Anti-Arrhythmia Agents, Antihypertensive Agents |
CAS number: | 22664-55-7 |
Indication: | Indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open angle glaucoma. |
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Pharmacology: |
Metipranolol is a beta1 and beta2 (non-selective) adrenergic receptor-blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane-stabilizing) activity. Metipranolol is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-ang...
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Mechanism of Action: |
Although it is known that metipranolol binds the beta1 and beta2 adrenergic receptors, the mechanism of metipranolol's action is not known. It has no significant intrinsic sympathomimetic activity, and has only weak local anesthetic (membrane-stabilizing) and myocardial depressant activity. It appears that the ophthalmic beta-adrenergic blocking ag...
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Affected organisms: | Humans and other mammals |
Drug interaction: |
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