QuickView for NAPB;jsessionid=C91F7C9853544C051ED33C2A944601D7 (gene)

Gene Symbol:

NAPB Homo sapiens

Full name:

NSF attachment protein beta

Synonyms:

SNAP-BETA, SNAPB, beta-soluble NSF attachment protein, N-ethylmaleimide-sensitive factor attachment protein, beta

Genomic Location:

Chr 20: 23303165-23350081

Description:

This gene encodes a member of the soluble N-ethyl-maleimide-sensitive fusion attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. This gene encodes the SNAP beta isoform which has been shown to be preferentially expressed in brain ti...

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This gene encodes a member of the soluble N-ethyl-maleimide-sensitive fusion attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. This gene encodes the SNAP beta isoform which has been shown to be preferentially expressed in brain tissue. The encoded protein also interacts with the GluR2 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit C-terminus and may play a role as a chaperone in the molecular processing of the AMPA receptor.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTTGCAC_MIR19A_MIR19B ,  TGANTCA_AP1_C ,  TGTGTGA_MIR377 ,  GGAMTNNNNNTCCY_UNKNOWN ,  IRF1_Q6 ,  STAT3_02 ,  GGGYGTGNY_UNKNOWN ,  ACTAYRNNNCCCR_UNKNOWN ,  TGCCAAR_NF1_Q6 ,  AAAYRNCTG_UNKNOWN ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  IK2_01 ,  IK1_01 ,  RCGCANGCGY_NRF1_Q6 ,  CAGCTG_AP4_Q5

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-377

Cytogenetic Map:

20p11.21

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