QuickView for NASP;jsessionid=DF3FB09F3D48514796170E68146687DE (gene)

Gene Symbol:

NASP Homo sapiens

Full name:

nuclear autoantigenic sperm protein

Synonyms:

FLB7527, HMDRA1, PRO1999, nuclear autoantigenic sperm protein, NASP histone chaperone, histone H1-binding protein, nuclear autoantigenic sperm protein (histone-binding)

Genomic Location:

Chr 1: 45822304-45857154

Description:

This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryon...

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This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  NFMUE1_Q6 ,  TGANTCA_AP1_C ,  STAT1_02 ,  ETS_Q4 ,  RYTTCCTG_ETS2_B ,  E2F1_Q4_01 ,  E2F4DP1_01 ,  CATTGTYY_SOX9_B1 ,  TEL2_Q6 ,  E2F_Q6_01 ,  E2F_01 ,  GCCATNTTG_YY1_Q6 ,  E2F1_Q4 ,  SOX9_B1 ,  E2F_Q6 ,  YY1_Q6 ,  E2F1_Q6_01 ,  SP1_Q4_01 ,  E2F_Q4 ,  ATTCTTT_MIR186 ,  GGGCGGR_SP1_Q6 ,  GGCNKCCATNK_UNKNOWN ,  E2F1DP2_01 ,  AAGWWRNYGGC_UNKNOWN ,  MGGAAGTG_GABP_B ,  CTTTAAR_UNKNOWN ,  SOX5_01 ,  E2F_03 ,  GGCNNMSMYNTTG_UNKNOWN ,  E2F1DP1_01 ,  E2F_Q4_01 ,  CETS1P54_01 ,  TTGTTT_FOXO4_01 ,  E2F1DP1RB_01 ,  SCGGAAGY_ELK1_02 ,  YY1_02 ,  E2F_02 ,  TATA_01 ,  E2F1_Q3 ,  TCCATTKW_UNKNOWN ,  E2F4DP2_01 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  E2F_Q3 ,  E2F_Q3_01 ,  ELF1_Q6 ,  E2F1_Q6 ,  SGCGSSAAA_E2F1DP2_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-29

Cytogenetic Map:

1p34.1

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