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QuickView for NAT2 (gene)
- Gene Symbol:
- NAT2
Homo sapiens - Full name:
- N-acetyltransferase 2
- Synonyms:
- AAC2, NAT-2, PNAT, arylamine N-acetyltransferase 2, N-acetyltransferase 2 (arylamine N-acetyltransferase), N-acetyltransferase type 2, arylamide acetylase 2
- Genomic Location:
- Chr 8: 18293035-18303003
- Description:
-
This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with hig...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
8p22
GO Molecular Function
N-acetyltransferase activity | arylamine N-acetyltransferase activity | transferase activity, transferring acyl groups other than amino-acyl groups | N-acyltransferase activity | catalytic activity | transferase activity, transferring acyl groups | protein binding | transferase activity | acetyltransferase activity
GO Biological Process
cellular process | xenobiotic metabolic process | response to stimulus | cellular response to xenobiotic stimulus | response to xenobiotic stimulus | metabolic process | cellular metabolic process
GO Cellular Component
cell | cytoplasm | cytosol | intracellular
