QuickView for NDUFA12 (gene)

Gene Symbol:

NDUFA12 Homo sapiens

Full name:

NADH:ubiquinone oxidoreductase subunit A12

Synonyms:

B17.2, DAP13, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12, 13 kDa differentiation-associated protein, CI-B17.2, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12, NADH-ubiquinone oxidoreductase subunit B17.2, complex I B17.2 subunit

Genomic Location:

Chr 12: 93889240-93921642

Description:

This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. ...

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This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YGTCCTTGR_UNKNOWN

Cytogenetic Map:

12q22

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