QuickView for NDUFA13 (gene)

Gene Symbol:

NDUFA13 Homo sapiens

Full name:

NADH:ubiquinone oxidoreductase subunit A13

Synonyms:

B16.6, CDA016, CGI-39, GRIM-19, GRIM19, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, CI-B16.6, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13, NADH-ubiquinone oxidoreductase B16.6 subunit, cell death regulatory protein GRIM-19, cell death-regulatory protein GRIM19, complex I B16.6 subunit, complex I-B16.6, gene associated with retinoic and IFN-induced mortality 19 protein, gene associated with retinoic and interferon-induced mortality 19 protein

Genomic Location:

Chr 19: 19487540-19500073

Description:

This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3)...

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This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGANTCA_AP1_C ,  AP1_Q6_01 ,  GTGACGY_E4F1_Q6 ,  GGGCGGR_SP1_Q6 ,  AHR_Q5 ,  TGCCAAR_NF1_Q6 ,  YGCGYRCGC_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  RCGCANGCGY_NRF1_Q6 ,  PAX2_02

Cytogenetic Map:

19p13.11

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