QuickView for NDUFB3 (gene)

Gene Symbol:

NDUFB3 Homo sapiens

Full name:

NADH:ubiquinone oxidoreductase subunit B3

Synonyms:

B12, CI-B12, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3, NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa, NADH-ubiquinone oxidoreductase B12 subunit, complex I-B12

Genomic Location:

Chr 2: 201644779-201658710

Description:

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial compl...

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This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein. Humans have multiple pseudogenes of this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGACCTY_ERR1_Q2 ,  ALPHACP1_01 ,  WTTGKCTG_UNKNOWN ,  CTGCAGY_UNKNOWN ,  ER_Q6_01

Cytogenetic Map:

2q33.1

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