QuickView for NDUFB9 (gene)

Gene Symbol:

NDUFB9 Homo sapiens

Full name:

NADH:ubiquinone oxidoreductase subunit B9

Synonyms:

B22, CI-B22, LYRM3, UQOR22, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9, LYR motif-containing protein 3, NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa, NADH-ubiquinone oxidoreductase B22 subunit, complex I B22 subunit

Genomic Location:

Chr 8: 125620524-125631408

Description:

The protein encoded by this gene is a subunit of the mitochondrial oxidative phosphorylation complex I (nicotinamide adenine dinucleotide: ubiquinone oxidoreductase). Complex I is localized to the inner mitochondrial membrane and functions to dehydrogenate nicotinamide adenine dinucleotide and to shuttle electrons to coenzyme Q. Complex I deficienc...

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The protein encoded by this gene is a subunit of the mitochondrial oxidative phosphorylation complex I (nicotinamide adenine dinucleotide: ubiquinone oxidoreductase). Complex I is localized to the inner mitochondrial membrane and functions to dehydrogenate nicotinamide adenine dinucleotide and to shuttle electrons to coenzyme Q. Complex I deficiency is the most common defect found in oxidative phosphorylation disorders and results in a range of conditions, including lethal neonatal disease, hypertrophic cardiomyopathy, liver disease, and adult-onset neurodegenerative disorders. Pseudogenes of this gene are found on chromosomes five, seven and eight. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  NFKAPPAB65_01 ,  GGATTA_PITX2_Q2 ,  CREL_01

Cytogenetic Map:

8q24.13

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