QuickView for NDUFC1 (gene)
- Gene Symbol:
- NDUFC1
Homo sapiens - Full name:
- NADH:ubiquinone oxidoreductase subunit C1
- Synonyms:
- KFYI, NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial, CI-KFYI, NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa, NADH-ubiquinone oxidoreductase KFYI subunit, complex I KFYI subunit, complex I-KFYI
- Genomic Location:
- Chr 4: 140430541-140436407
- Description:
-
The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
4q31.1
| Transcripts Names |
|---|
| NM_002494 |
| NM_001184986 |
| NM_001184987 |
| NM_001184991 |
| NM_001184989 |
| NM_001184988 |
| NM_001184990 |
GO Molecular Function
oxidoreductase activity, acting on NAD(P)H | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | catalytic activity | NADH dehydrogenase activity | NADH dehydrogenase (ubiquinone) activity | oxidoreductase activity
GO Biological Process
purine ribonucleotide metabolic process | oxidoreductase activity, acting on NAD(P)H | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | generation of precursor metabolites and energy | cellular process | nucleotide metabolic process | ATP synthesis coupled electron transport | cellular respiration | ribose phosphate metabolic process | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | organic cyclic compound metabolic process | mitochondrial respiratory chain complex assembly | cellular aromatic compound metabolic process | cellular component organization | purine nucleotide metabolic process | mitochondrial respiratory chain complex I assembly | electron transport chain | cellular nitrogen compound metabolic process | cellular component assembly | mitochondrion organization | nitrogen compound metabolic process | phosphorus metabolic process | organophosphate metabolic process | NADH dehydrogenase complex assembly | small molecule metabolic process | nucleobase-containing small molecule metabolic process | phosphorylation | cellular protein-containing complex assembly | phosphate-containing compound metabolic process | mitochondrial ATP synthesis coupled electron transport | drug metabolic process | protein-containing complex assembly | NADH dehydrogenase activity | metabolic process | oxidation-reduction process | oxidative phosphorylation | nucleobase-containing compound metabolic process | organic substance metabolic process | NADH dehydrogenase (ubiquinone) activity | energy derivation by oxidation of organic compounds | organelle organization | carbohydrate derivative metabolic process | mitochondrial electron transport, NADH to ubiquinone | heterocycle metabolic process | cellular metabolic process | ATP metabolic process | oxidoreductase activity | respiratory electron transport chain
GO Cellular Component
integral component of membrane | organelle inner membrane | intracellular membrane-bounded organelle | catalytic complex | mitochondrial inner membrane | organelle membrane | cell | oxidoreductase complex | mitochondrial respiratory chain complex I | intrinsic component of membrane | cytoplasm | respiratory chain complex I | intracellular organelle | protein-containing complex | mitochondrial respiratory chain | respiratory chain | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane
