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QuickView for NDUFS5 (gene)


Gene Symbol:
NDUFS5 Homo sapiens Homo sapiens
Full name:
NADH:ubiquinone oxidoreductase subunit S5
Synonyms:
CI-15k, CI15K, NADH dehydrogenase [ubiquinone] iron-sulfur protein 5, CI-15 kDa, NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase), NADH:ubiquinone oxidoreductase 15 kDa IP subunit, complex I-15 kDa
Genomic Location:
Chr 1: 39264593-39272874
Description:
This gene is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family. The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants and pseudogene...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes Canis lupus familiaris Danio rerio Gallus gallus
External Links:
Entrez Gene
Cytogenetic Map:
chr 1
1p34.3


Transcripts Names
NM_004552
NM_001184979
Protein Names
O43920
Q6IBA0



GO Molecular Function

oxidoreductase activity, acting on NAD(P)H | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | catalytic activity | NADH dehydrogenase activity | NADH dehydrogenase (ubiquinone) activity | oxidoreductase activity

GO Biological Process

purine ribonucleotide metabolic process | oxidoreductase activity, acting on NAD(P)H | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | generation of precursor metabolites and energy | cellular process | nucleotide metabolic process | ATP synthesis coupled electron transport | cellular respiration | ribose phosphate metabolic process | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | organic cyclic compound metabolic process | mitochondrial respiratory chain complex assembly | cellular aromatic compound metabolic process | cellular component organization | purine nucleotide metabolic process | mitochondrial respiratory chain complex I assembly | electron transport chain | cellular nitrogen compound metabolic process | cellular component assembly | mitochondrion organization | nitrogen compound metabolic process | phosphorus metabolic process | organophosphate metabolic process | NADH dehydrogenase complex assembly | small molecule metabolic process | nucleobase-containing small molecule metabolic process | phosphorylation | cellular protein-containing complex assembly | phosphate-containing compound metabolic process | mitochondrial ATP synthesis coupled electron transport | drug metabolic process | protein-containing complex assembly | NADH dehydrogenase activity | metabolic process | oxidation-reduction process | oxidative phosphorylation | nucleobase-containing compound metabolic process | organic substance metabolic process | NADH dehydrogenase (ubiquinone) activity | energy derivation by oxidation of organic compounds | organelle organization | carbohydrate derivative metabolic process | mitochondrial electron transport, NADH to ubiquinone | heterocycle metabolic process | cellular metabolic process | ATP metabolic process | oxidoreductase activity | respiratory electron transport chain

GO Cellular Component

mitochondrial intermembrane space | organelle inner membrane | intracellular membrane-bounded organelle | catalytic complex | mitochondrial inner membrane | organelle membrane | cell | oxidoreductase complex | mitochondrial respiratory chain complex I | cytoplasm | respiratory chain complex I | intracellular organelle | protein-containing complex | mitochondrial respiratory chain | respiratory chain | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | membrane-enclosed lumen | mitochondrial membrane | intracellular | membrane