QuickView for NGF (gene)

Gene Symbol:

NGF Homo sapiens

Full name:

nerve growth factor

Synonyms:

Beta-NGF, HSAN5, NGFB, beta-nerve growth factor, nerve growth factor (beta polypeptide), nerve growth factor, beta subunit

Genomic Location:

Chr 1: 115630060-115682380

Description:

This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been ass...

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This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  POU6F1_01 ,  GCANCTGNY_MYOD_Q6 ,  VDR_Q6 ,  LFA1_Q6 ,  CAGGTG_E12_Q6 ,  AREB6_03 ,  RTTTNNNYTGGM_UNKNOWN ,  CAGCTG_AP4_Q5 ,  CP2_01

Cytogenetic Map:

1p13.2

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