QuickView for NHERF2 (gene)

Gene Symbol:

SLC9A3R2 Homo sapiens

Full name:

SLC9A3 regulator 2

Synonyms:

E3KARP, NHE3RF2, NHERF-2, NHERF2, OCTS2, SIP-1, SIP1, TKA-1, Na(+)/H(+) exchange regulatory cofactor NHE-RF2, NHE3 kinase A regulatory protein E3KARP, NHE3 regulatory factor 2, SRY-interacting protein 1, sodium/hydrogen exchanger 3 kinase A regulatory protein, solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2, solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 2, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2, solute carrier family 9 isoform A3 regulatory factor 2, solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2, tyrosine kinase activator protein 1

Genomic Location:

Chr 16: 2016930-2028484

Description:

This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of ...

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This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YGCANTGCR_UNKNOWN

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-25

Cytogenetic Map:

16p13.3

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