QuickView for NIS (gene)

Gene Symbol:

SLC5A5 Homo sapiens

Full name:

solute carrier family 5 member 5

Synonyms:

NIS, TDH1, sodium/iodide cotransporter, Na(+)/I(-) cotransporter, Na(+)/I(-) symporter, solute carrier family 5 (sodium iodide symporter), member 5, solute carrier family 5 (sodium/iodide cotransporter), member 5

Genomic Location:

Chr 19: 17843782-17865897

Description:

This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are ...

View Full Description

This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Cytogenetic Map:

19p13.11

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