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QuickView for NK1 receptor (gene)


Gene Symbol:
Tacr1 Mus musculus Mus musculus
Full name:
tachykinin receptor 1
Synonyms:
Nk1r, Spr, Tac1r, substance-P receptor, Nk1 receptor, neurokinin receptor 1, substance P receptor
Genomic Location:
Chr 6: 82352469-82510093
Description:
This gene encodes the receptor for the tachykinin, substance P, also referred to as neurokinin 1. This gene belongs to a gene family of tachykinin receptors which are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This receptor has been associated with nitric oxide formation, and it has been local...
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Protein Names
P30548
Q8BYR7



GO Molecular Function

tachykinin receptor activity | transmembrane signaling receptor activity | G-protein coupled receptor activity | neuropeptide receptor activity | substance P receptor activity | signaling receptor activity | peptide receptor activity | G-protein coupled peptide receptor activity

GO Biological Process

behavioral response to pain | regulation of supramolecular fiber organization | positive regulation of action potential | regulation of blood vessel diameter | regulation of muscle system process | tachykinin receptor activity | positive regulation of locomotion | positive regulation of blood circulation | regulation of systemic arterial blood pressure by hormone | long-term memory | positive regulation of cellular component organization | regulation of localization | insemination | regulation of immune system process | response to hormone | positive regulation of lymphocyte activation | positive regulation of epithelial cell proliferation | regulation of smooth muscle contraction | response to drug | cellular chemical homeostasis | regulation of organelle organization | positive regulation of cellular component movement | regulation of renal sodium excretion | response to antibiotic | cellular process | neuropeptide signaling pathway | regulation of cell motility | cellular homeostasis | positive regulation of synaptic transmission | regulation of digestive system process | multicellular organismal reproductive process | learning | response to inorganic substance | drinking behavior | positive regulation of vasoconstriction | positive regulation of uterine smooth muscle contraction | regulation of cellular process | regulation of cytosolic calcium ion concentration | neurological system process involved in regulation of systemic arterial blood pressure | positive regulation of renal sodium excretion | smooth muscle contraction | regulation of systemic arterial blood pressure mediated by a chemical signal | calcium ion homeostasis | positive regulation of epithelial cell migration | G-protein coupled receptor activity | muscle contraction | associative learning | response to stimulus | positive regulation of blood pressure | response to pain | positive regulation of immune system process | positive regulation of flagellated sperm motility | regulation of excretion | positive regulation of saliva secretion | regulation of blood vessel size | response to stress | positive regulation of lymphocyte proliferation | response to ozone | regulation of cell proliferation | positive regulation of actin filament bundle assembly | regulation of blood circulation | regulation of smooth muscle cell migration | positive regulation of cell activation | reproduction | response to alcohol | response to temperature stimulus | neuropeptide receptor activity | positive regulation of hormone secretion | blood circulation | G-protein coupled receptor signaling pathway | modulation of chemical synaptic transmission | metal ion homeostasis | urinary bladder smooth muscle contraction | response to ethanol | positive regulation of stress fiber assembly | regulation of membrane potential | positive regulation of mononuclear cell proliferation | response to nicotine | reproductive process | positive regulation of organelle organization | regulation of synaptic transmission, cholinergic | regulation of actin cytoskeleton organization | regulation of synaptic transmission, GABAergic | regulation of actin filament organization | learning or memory | tachykinin receptor signaling pathway | regulation of muscle contraction | regulation of actomyosin structure organization | regulation of hormone levels | regulation of hormone secretion | regulation of ossification | regulation of flagellated sperm motility | positive regulation of secretion | nervous system process | copulation | regulation of blood pressure | excretion | regulation of systemic arterial blood pressure by renin-angiotensin | regulation of systemic arterial blood pressure | regulation of lymphocyte activation | cellular ion homeostasis | substance P receptor activity | aggressive behavior | positive regulation of cytosolic calcium ion concentration | regulation of cell migration | regulation of vascular permeability | regulation of cellular component movement | response to oxidative stress | positive regulation of digestive system process | cognition | positive regulation of cell migration | regulation of uterine smooth muscle contraction | sensory perception of pain | eating behavior | positive regulation of ossification | regulation of blood volume by renin-angiotensin | response to toxic substance | cation homeostasis | regulation of leukocyte migration | cellular cation homeostasis | endocrine process | cell communication | positive regulation of smooth muscle contraction | positive regulation of cytoskeleton organization | smooth muscle contraction involved in micturition | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | regulation of locomotion | positive regulation of synaptic transmission, GABAergic | regulation of tube size | positive regulation of transport | sperm ejaculation | multicellular organism reproduction | multicellular organismal response to stress | angiotensin-mediated drinking behavior | response to organic substance | response to mechanical stimulus | regulation of saliva secretion | positive regulation of vascular permeability | regulation of vasoconstriction | positive regulation of supramolecular fiber organization | positive regulation of leukocyte activation | regulation of body fluid levels | regulation of tube diameter | chemical homeostasis | brain renin-angiotensin system | regulation of secretion | behavior | positive regulation of muscle contraction | positive regulation of cellular component biogenesis | mating | response to reactive oxygen species | regulation of cell activation | positive regulation of leukocyte migration | micturition | response to heat | ion homeostasis | renal system process | positive regulation of synaptic transmission, cholinergic | regulation of stress fiber assembly | memory | sensory perception | regulation of epithelial cell migration | regulation of action potential | regulation of cell communication | signaling | feeding behavior | G-protein coupled peptide receptor activity | response to organic cyclic compound | regulation of epithelial cell proliferation | operant conditioning | regulation of actin filament bundle assembly | regulation of transport | cellular metal ion homeostasis | regulation of actin filament-based process | regulation of smooth muscle cell proliferation | positive regulation of cell motility | divalent inorganic cation homeostasis | sexual reproduction | regulation of cellular component organization | regulation of cytoskeleton organization | muscle system process | positive regulation of signaling | signal transduction | regulation of signaling | response to auditory stimulus | multicellular organismal process

GO Cellular Component

sperm flagellum | integral component of membrane | dendrite | sperm midpiece | neuron projection | somatodendritic compartment | cell body | cell | intrinsic component of membrane | cytoplasm | 9+2 motile cilium | motile cilium | dendritic tree | cell projection | plasma membrane | cilium | organelle | cell periphery | cell surface | intracellular | membrane | sperm head