QuickView for NKX6-2 (gene)
- Gene Symbol:
- NKX6-2
Homo sapiens - Full name:
- NK6 homeobox 2
- Synonyms:
- GTX, NKX6.2, NKX6B, SPAX8, homeobox protein Nkx-6.2, NK homeobox family 6, B, NK6 transcription factor related, locus 2, glial and testis-specific homeobox protein, homeobox 6B, homeobox protein NK-6 homolog B
- Genomic Location:
- Chr 10: 134448310-134449527
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
GATTGGY_NFY_Q6_01 , GATA1_03 , GCANCTGNY_MYOD_Q6 , NFY_Q6_01 , ALPHACP1_01 , CAGGTG_E12_Q6 , MYOD_Q6 , NFY_01 , E2F1_Q3_01 , NFY_Q6
- Cytogenetic Map:
-
10q26.3
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
regulation of neurogenesis | regulation of cell development | spinal cord motor neuron differentiation | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cell differentiation | ventral spinal cord interneuron fate commitment | nervous system development | neurogenesis | generation of neurons | neuromuscular process controlling balance | pattern specification process | cellular process | negative regulation of gliogenesis | cell fate specification | axon ensheathment | central nervous system neuron differentiation | negative regulation of nucleic acid-templated transcription | regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification | central nervous system myelination | negative regulation of cellular metabolic process | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | gliogenesis | endocrine pancreas development | spinal cord motor neuron cell fate specification | oligodendrocyte development | spinal cord dorsal/ventral patterning | ensheathment of neurons | axon ensheathment in central nervous system | ventral spinal cord interneuron specification | positive regulation of gliogenesis | negative regulation of metabolic process | dorsal/ventral pattern formation | neuron fate commitment | regulation of nucleic acid-templated transcription | system development | ventral spinal cord development | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification | myelination | multicellular organism development | regulation of gene expression | pancreas development | nervous system process | regulation of myelination | regulation of nitrogen compound metabolic process | cell fate specification involved in pattern specification | regulation of transcription by RNA polymerase II | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | positive regulation of cell differentiation | glial cell differentiation | endocrine system development | ventral spinal cord interneuron differentiation | regulation of cellular metabolic process | regulation of RNA metabolic process | cell fate commitment involved in pattern specification | negative regulation of cell fate commitment | neuron differentiation | DNA-binding transcription factor activity | regionalization | anatomical structure development | positive regulation of neurogenesis | positive regulation of cell development | cell fate commitment | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | oligodendrocyte differentiation | positive regulation of glial cell differentiation | spinal cord patterning | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | regulation of transcription involved in cell fate commitment | cell differentiation in spinal cord | regulation of glial cell differentiation | regulation of gliogenesis | regulation of transcription, DNA-templated | glial cell development | neuromuscular process | cell development | regulation of nervous system development | regulation of developmental process | developmental process | negative regulation of glial cell differentiation | negative regulation of transcription by RNA polymerase II | positive regulation of cell fate commitment | regulation of cell fate commitment | central nervous system development | spinal cord development | negative regulation of cell development | neuron fate specification | negative regulation of cell differentiation | negative regulation of neurogenesis | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
