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QuickView for NLGN4X;jsessionid=71E361B6A21B5712E455C0DB91BE6503 (gene)


Gene Symbol:
NLGN4X Homo sapiens Homo sapiens
Full name:
neuroligin 4, X-linked
Synonyms:
ASPGX2, AUTSX2, HLNX, HNL4X, NLGN4, neuroligin-4, X-linked
Genomic Location:
Chr X: 5818083-6156706
Description:
This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein inte...
Orthologs:
D. melanogaster Macaca mulatta Gallus gallus Canis lupus familiaris
External Links:
Entrez Gene
Cytogenetic Map:
chr X
Xp22.32-p22.31





GO Molecular Function

signaling receptor binding | neurexin family protein binding | anion binding | chloride ion binding | signaling receptor activity | identical protein binding | scaffold protein binding | ion binding | cell adhesion molecule binding | protein binding | protein homodimerization activity | protein dimerization activity

GO Biological Process

brain development | negative regulation of excitatory postsynaptic potential | establishment of localization | negative regulation of cellular process | social behavior | cell differentiation | nervous system development | organ growth | neurogenesis | generation of neurons | membrane organization | membrane biogenesis | cellular process | localization | negative regulation of signaling | developmental growth | synapse assembly | learning | establishment of localization in cell | regulation of neurological system process | regulation of cellular process | cellular component organization | head development | metencephalon development | negative regulation of neurological system process | postsynaptic membrane assembly | cellular localization | cellular component assembly | modulation of chemical synaptic transmission | presynaptic membrane assembly | regulation of membrane potential | synaptic vesicle cycle | system development | brainstem development | regulation of signal transduction | modulation of excitatory postsynaptic potential | multicellular organism development | learning or memory | cerebellum development | neuron cell-cell adhesion | synaptic vesicle recycling | nervous system process | membrane assembly | vesicle-mediated transport | synapse organization | cognition | hindbrain development | postsynapse assembly | presynaptic membrane organization | synaptic vesicle endocytosis | postsynaptic membrane organization | neuron differentiation | presynapse assembly | import into cell | anatomical structure development | endocytosis | behavior | cell adhesion | vocalization behavior | animal organ development | cell-cell adhesion | adult behavior | regulation of cell communication | negative regulation of signal transduction | developmental process | negative regulation of synaptic transmission | central nervous system development | regulation of signaling | multicellular organismal process | cell-cell junction organization

GO Cellular Component

integral component of membrane | dendrite | synapse | spanning component of membrane | neuron projection | somatodendritic compartment | symmetric synapse | cell | intrinsic component of membrane | synaptic membrane | dendritic tree | cell projection | postsynaptic membrane | postsynapse | plasma membrane | postsynaptic density | asymmetric synapse | integral component of plasma membrane | asymmetric, glutamatergic, excitatory synapse | organelle | postsynaptic specialization | inhibitory synapse | glutamatergic synapse | cell periphery | excitatory synapse | GABA-ergic synapse | symmetric, GABA-ergic, inhibitory synapse | cell surface | cell junction | membrane | intrinsic component of plasma membrane