QuickView for NLRC4 (gene)

Gene Symbol:

NLRC4 Homo sapiens

Full name:

NLR family CARD domain containing 4

Synonyms:

AIFEC, CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, FCAS4, IPAF, NLR family CARD domain-containing protein 4, CARD, LRR, and NACHT-containing protein, ICE-protease activating factor, NOD-like receptor C4, caspase recruitment domain family, member 12, caspase recruitment domain-containing protein 12, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4

Genomic Location:

Chr 2: 32303022-32344305

Description:

This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple...

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This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AP1_Q2

Cytogenetic Map:

2p22.3

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