QuickView for NLRP7 (gene)

Gene Symbol:

NLRP7 Homo sapiens

Full name:

NLR family pyrin domain containing 7

Synonyms:

CLR19.4, HYDM, NALP7, NOD12, PAN7, PYPAF3, NACHT, LRR and PYD domains-containing protein 7, NACHT, LRR and PYD containing protein 7, NACHT, leucine rich repeat and PYD containing 7, PYRIN-containing Apaf1-like protein 3, nucleotide-binding oligomerization domain protein 12, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7

Genomic Location:

Chr 19: 60126689-60150679

Description:

This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein com...

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This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Orthologs:

Macaca mulatta ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YCATTAA_UNKNOWN

Cytogenetic Map:

19q13.42

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