QuickView for NOP56;jsessionid=F7402770BB61156DD2B37E9C7D478CE9 (gene)

Gene Symbol:

NOP56 Homo sapiens

Full name:

NOP56 ribonucleoprotein

Synonyms:

NOL5A, SCA36, nucleolar protein 56, NOP56 ribonucleoprotein homolog, nucleolar protein 5A (56kDa with KKE/D repeat)

Genomic Location:

Chr 20: 2581254-2587039

Description:

Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from...

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Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  USF_Q6 ,  CACGTG_MYC_Q2 ,  YGCANTGCR_UNKNOWN ,  MYCMAX_01 ,  NFY_01 ,  NMYC_01 ,  TGACAGNY_MEIS1_01

Cytogenetic Map:

20p13

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