Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for NPR1 (gene)


Gene Symbol:
NPR1 Homo sapiens Homo sapiens
Full name:
natriuretic peptide receptor 1
Synonyms:
ANPRA, ANPa, GUC2A, GUCY2A, NPRA, atrial natriuretic peptide receptor 1, ANP-A, ANPR-A, GC-A, NPR-A, atrial natriuretic peptide receptor type A, atrionatriuretic peptide receptor A, guanylate cyclase A, natriuretic peptide A type receptor, natriuretic peptide receptor A, natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A), testicular tissue protein Li 20
Genomic Location:
Chr 1: 151917737-151933088
Description:
Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a sin...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1
1q21.3





GO Molecular Function

kinase binding | guanyl ribonucleotide binding | ribonucleoside binding | peptide binding | peptide hormone binding | protein kinase binding | guanylate cyclase activity | transmembrane signaling receptor activity | enzyme binding | ribonucleotide binding | nucleotide binding | G-protein coupled receptor activity | carbohydrate derivative binding | lyase activity | natriuretic peptide receptor activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | amide binding | signaling receptor activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine nucleoside binding | hormone binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | GTP binding | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | nucleoside binding | peptide receptor activity | G-protein coupled peptide receptor activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | phosphorus-oxygen lyase activity | heterocyclic compound binding | guanyl nucleotide binding | small molecule binding | cyclase activity

GO Biological Process

purine ribonucleotide metabolic process | regulation of blood vessel diameter | cyclic nucleotide biosynthetic process | intracellular signal transduction | regulation of localization | catechol-containing compound metabolic process | establishment of localization | negative regulation of cellular process | regulation of renal sodium excretion | phenol-containing compound metabolic process | cellular process | secretion | localization | cGMP biosynthetic process | receptor guanylyl cyclase signaling pathway | nucleotide metabolic process | ribose phosphate metabolic process | purine nucleotide biosynthetic process | guanylate cyclase activity | ribonucleotide metabolic process | regulation of angiogenesis | regulation of cellular process | organic cyclic compound metabolic process | positive regulation of renal sodium excretion | cellular aromatic compound metabolic process | regulation of urine volume | G-protein coupled receptor activity | regulation of vasculature development | response to stimulus | purine nucleotide metabolic process | regulation of excretion | regulation of blood vessel size | cellular nitrogen compound biosynthetic process | cyclic purine nucleotide metabolic process | regulation of cell proliferation | negative regulation of angiogenesis | regulation of blood circulation | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | blood circulation | G-protein coupled receptor signaling pathway | protein modification process | cellular biosynthetic process | macromolecule modification | dopamine metabolic process | nucleotide biosynthetic process | organic hydroxy compound metabolic process | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of urine volume | negative regulation of growth | phosphorus metabolic process | cyclic nucleotide metabolic process | regulation of cGMP-mediated signaling | positive regulation of secretion | regulation of blood pressure | organophosphate metabolic process | negative regulation of smooth muscle cell proliferation | enzyme linked receptor protein signaling pathway | small molecule metabolic process | regulation of vascular permeability | positive regulation of intracellular signal transduction | cGMP metabolic process | nucleobase-containing small molecule metabolic process | biosynthetic process | aromatic compound biosynthetic process | phosphorylation | purine ribonucleotide biosynthetic process | regulation of heart contraction | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | positive regulation of signal transduction | regulation of tube size | positive regulation of transport | negative regulation of cell growth | drug metabolic process | protein metabolic process | regulation of growth | catecholamine metabolic process | regulation of intracellular signal transduction | cell surface receptor signaling pathway | metabolic process | positive regulation of cGMP-mediated signaling | regulation of body fluid levels | regulation of tube diameter | regulation of secretion | body fluid secretion | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | renal system process | regulation of cell communication | signaling | G-protein coupled peptide receptor activity | ribose phosphate biosynthetic process | cellular protein metabolic process | regulation of developmental process | kinase activity | regulation of cell growth | regulation of cardiac conduction | cellular protein modification process | carbohydrate derivative metabolic process | regulation of transport | negative regulation of cell proliferation | negative regulation of vasculature development | heterocycle metabolic process | cellular metabolic process | regulation of smooth muscle cell proliferation | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | receptor complex | protein-containing complex | plasma membrane | cell periphery | membrane