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QuickView for NR2D (gene)


Gene Symbol:
GRIN2D Homo sapiens Homo sapiens
Full name:
glutamate ionotropic receptor NMDA type subunit 2D
Synonyms:
EB11, EIEE46, GluN2D, NMDAR2D, NR2D, glutamate receptor ionotropic, NMDA 2D, N-methyl D-aspartate receptor subtype 2D, N-methyl-d-aspartate receptor subunit 2D, estrogen receptor binding CpG island, glutamate [NMDA] receptor subunit epsilon-4, glutamate receptor, ionotropic, N-methyl D-aspartate 2D
Genomic Location:
Chr 19: 53589944-53640000
Description:
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key recep...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 19
19q13.33


Transcripts Names
NM_000836
XM_011526872
Protein Names
Q59G17
O15399



GO Molecular Function

transmitter-gated ion channel activity | guanyl-nucleotide exchange factor activity | ligand-gated calcium channel activity | neurotransmitter receptor activity | GTPase binding | voltage-gated ion channel activity | passive transmembrane transporter activity | transmembrane signaling receptor activity | enzyme binding | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | Ras GTPase binding | molecular function regulator | NMDA glutamate receptor activity | cation transmembrane transporter activity | signaling receptor activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | glutamate receptor activity | protein binding | ionotropic glutamate receptor activity | metal ion transmembrane transporter activity | voltage-gated cation channel activity | Ras guanyl-nucleotide exchange factor activity | small GTPase binding | cation channel activity | glutamate-gated calcium ion channel activity | inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | calcium channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

transmitter-gated ion channel activity | brain development | guanyl-nucleotide exchange factor activity | intracellular signal transduction | calcium ion transmembrane import into cytosol | cytosolic calcium ion transport | ligand-gated calcium channel activity | establishment of localization | excitatory postsynaptic potential | nervous system development | cellular chemical homeostasis | voltage-gated ion channel activity | cellular process | localization | cellular homeostasis | positive regulation of synaptic transmission | passive transmembrane transporter activity | metal ion transport | chemical synaptic transmission | establishment of localization in cell | regulation of neurological system process | regulation of cellular process | regulation of cytosolic calcium ion concentration | transmembrane transporter activity | ligand-gated ion channel activity | MAPK cascade | calcium ion homeostasis | head development | calcium ion transport into cytosol | response to stimulus | ion gated channel activity | signal transduction by protein phosphorylation | cellular localization | divalent metal ion transport | protein modification process | modulation of chemical synaptic transmission | macromolecule modification | cell-cell signaling | molecular function regulator | cell surface receptor signaling pathway involved in cell-cell signaling | metal ion homeostasis | regulation of membrane potential | system development | nitrogen compound metabolic process | multicellular organism development | calcium ion transmembrane transport | phosphorus metabolic process | ion transmembrane transport | regulation of sensory perception of pain | excitatory chemical synaptic transmission | regulation of postsynaptic membrane potential | nervous system process | synaptic signaling | NMDA glutamate receptor activity | cation transmembrane transporter activity | cellular ion homeostasis | adult locomotory behavior | positive regulation of cytosolic calcium ion concentration | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | second-messenger-mediated signaling | locomotory behavior | extracellular ligand-gated ion channel activity | phosphorylation | startle response | protein phosphorylation | cation homeostasis | phosphate-containing compound metabolic process | cellular cation homeostasis | cell communication | cellular calcium ion homeostasis | homeostatic process | calcium-mediated signaling | cation transmembrane transport | protein metabolic process | ionotropic glutamate receptor activity | metal ion transmembrane transporter activity | anatomical structure development | cell surface receptor signaling pathway | voltage-gated cation channel activity | metabolic process | chemical homeostasis | Ras guanyl-nucleotide exchange factor activity | calcium ion transport | behavior | organic substance metabolic process | animal organ development | ion homeostasis | inorganic cation transmembrane transport | cation channel activity | adult behavior | regulation of cell communication | transmembrane transport | glutamate-gated calcium ion channel activity | signaling | inorganic cation transmembrane transporter activity | neuromuscular process | voltage-gated channel activity | cellular protein metabolic process | cation transport | channel activity | glutamate receptor signaling pathway | developmental process | calcium channel activity | cellular protein modification process | cellular metal ion homeostasis | central nervous system development | ion channel activity | regulation of synaptic plasticity | ion transport | cellular metabolic process | long-term synaptic potentiation | ionotropic glutamate receptor signaling pathway | divalent inorganic cation homeostasis | substrate-specific channel activity | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | synapse | postsynaptic specialization membrane | cell | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | NMDA selective glutamate receptor complex | receptor complex | protein-containing complex | postsynaptic membrane | postsynapse | plasma membrane | postsynaptic density membrane | postsynaptic density | asymmetric synapse | integral component of plasma membrane | organelle | postsynaptic specialization | cell periphery | ionotropic glutamate receptor complex | transmembrane transporter complex | cation channel complex | ion channel complex | intracellular | cell junction | membrane | intrinsic component of plasma membrane