QuickView for NR5A2 (gene)

Gene Symbol:

NR5A2 Homo sapiens

Full name:

nuclear receptor subfamily 5 group A member 2

Synonyms:

B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, LRH1, hB1F-2, nuclear receptor subfamily 5 group A member 2, CYP7A promoter-binding factor, b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus, fetoprotein-alpha 1 (AFP) transcription factor, hepatocytic transcription factor hB1F-3, liver nuclear receptor homolog-1 variant 2

Genomic Location:

Chr 1: 198263393-198413175

Description:

The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development.

The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  TGGAAA_NFAT_Q4_01 ,  CTTGTAT_MIR381 ,  HNF1_01 ,  TTANTCA_UNKNOWN ,  TCANNTGAY_SREBP1_01 ,  GATA3_01 ,  GATA_Q6 ,  GATA_C ,  CIZ_01 ,  LXR_DR4_Q3 ,  TTTGTAG_MIR520D ,  HP1SITEFACTOR_Q6 ,  ARP1_01 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  TAAYNRNNTCC_UNKNOWN ,  GATAAGR_GATA_C ,  GATA1_04 ,  TGACCTY_ERR1_Q2 ,  ACTGTGA_MIR27A_MIR27B ,  CTTTGTA_MIR524 ,  TATAAA_TATA_01 ,  LFA1_Q6 ,  PXR_Q2 ,  TATA_C ,  HNF4_Q6 ,  RRAGTTGT_UNKNOWN ,  TGCCTTA_MIR124A ,  ATTCTTT_MIR186 ,  ACCAAAG_MIR9 ,  LMO2COM_02 ,  GATA6_01 ,  TAATAAT_MIR126 ,  CTTTAAR_UNKNOWN ,  GATA1_02 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  STAT5A_04 ,  GATA1_05 ,  RGTTAMWNATT_HNF1_01 ,  AACTTT_UNKNOWN ,  DR4_Q2 ,  CTCCAAG_MIR432

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-10 ,  Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-204 ,  Predicted Gene Targets for miR-208 ,  Predicted Gene Targets for miR-219 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-31 ,  Predicted Gene Targets for miR-375 ,  Predicted Gene Targets for miR-499

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Cytogenetic Map:

1q32.1

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