QuickView for NT5C2 (gene)
- Gene Symbol:
- NT5C2
Homo sapiens - Full name:
- 5'-nucleotidase, cytosolic II
- Synonyms:
- GMP, NT5B, PNT5, SPG45, SPG65, cN-II, cytosolic purine 5'-nucleotidase, 5'-nucleotidase (purine), cytosolic type B, IMP-specific 5'-NT
- Genomic Location:
- Chr 10: 104837902-104943006
- Description:
-
This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
10q24.32-q24.33
GO Molecular Function
nucleotidase activity | cation binding | nucleotide binding | phosphatase activity | nucleoside phosphotransferase activity | hydrolase activity | catalytic activity | hydrolase activity, acting on ester bonds | ion binding | nucleobase-containing compound kinase activity | organic cyclic compound binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphoric ester hydrolase activity | phosphotransferase activity, alcohol group as acceptor | transferase activity | 5'-nucleotidase activity | kinase activity | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
purine ribonucleotide metabolic process | nucleoside phosphate catabolic process | organophosphate catabolic process | nucleotidase activity | cellular process | organic substance catabolic process | nucleotide metabolic process | ribose phosphate metabolic process | ribonucleotide metabolic process | adenosine metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | phosphatase activity | purine nucleotide metabolic process | nucleoside phosphotransferase activity | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | purine nucleoside metabolic process | nucleobase-containing compound catabolic process | nitrogen compound metabolic process | phosphorus metabolic process | organophosphate metabolic process | nucleoside metabolic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | biosynthetic process | aromatic compound biosynthetic process | phosphorylation | nucleotide catabolic process | nucleobase-containing compound kinase activity | phosphate-containing compound metabolic process | aromatic compound catabolic process | drug metabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | organonitrogen compound catabolic process | dephosphorylation | 5'-nucleotidase activity | kinase activity | carbohydrate derivative metabolic process | heterocycle metabolic process | cellular metabolic process | IMP metabolic process | purine nucleotide catabolic process
GO Cellular Component
cell | cytoplasm | cytosol | intracellular
