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QuickView for NT5E (gene)


Gene Symbol:
NT5E Homo sapiens Homo sapiens
Full name:
5'-nucleotidase ecto
Synonyms:
CALJA, CD73, E5NT, NT, NT5, NTE, eN, eNT, 5'-nucleotidase, 5'-NT, Purine 5-Prime-Nucleotidase, ecto-5'-nucleotidase
Genomic Location:
Chr 6: 86216528-86262215
Description:
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different ...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 6
6q14.3


Transcripts Names
NM_002526
NM_001204813
Protein Names
B3KQI8
Q5W116
O75520
Q6NZX3
P21589



GO Molecular Function

nucleotidase activity | cation binding | nucleotide binding | phosphatase activity | hydrolase activity | catalytic activity | hydrolase activity, acting on ester bonds | ion binding | organic cyclic compound binding | phosphoric ester hydrolase activity | 5'-nucleotidase activity | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

purine ribonucleotide metabolic process | nucleoside phosphate catabolic process | pyrimidine nucleoside metabolic process | organophosphate catabolic process | nucleoside catabolic process | nucleotidase activity | cellular process | organic substance catabolic process | negative regulation of inflammatory response | nucleotide metabolic process | carbohydrate derivative catabolic process | ribose phosphate metabolic process | ribonucleotide metabolic process | adenosine metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | phosphatase activity | purine nucleotide metabolic process | AMP catabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | cofactor metabolic process | cellular biosynthetic process | purine nucleoside metabolic process | nucleobase-containing compound catabolic process | purine nucleoside monophosphate catabolic process | drug catabolic process | nitrogen compound metabolic process | phosphorus metabolic process | organophosphate metabolic process | nucleoside metabolic process | nucleobase-containing small molecule catabolic process | adenosine biosynthetic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | biosynthetic process | aromatic compound biosynthetic process | nucleotide catabolic process | phosphate-containing compound metabolic process | aromatic compound catabolic process | drug metabolic process | AMP metabolic process | DNA metabolic process | leukocyte cell-cell adhesion | metabolic process | cell adhesion | nucleobase-containing compound metabolic process | organic substance metabolic process | cell-cell adhesion | organonitrogen compound catabolic process | dephosphorylation | 5'-nucleotidase activity | nicotinamide nucleotide metabolic process | NAD metabolic process | carbohydrate derivative metabolic process | heterocycle metabolic process | purine ribonucleotide catabolic process | cellular metabolic process | regulation of inflammatory response | purine nucleotide catabolic process | macromolecule metabolic process | pyrimidine nucleoside catabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | intrinsic component of membrane | cytoplasm | intracellular organelle | nucleoplasm | plasma membrane | vesicle | extracellular exosome | anchored component of membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | cell periphery | membrane-enclosed lumen | cytosol | cell surface | intracellular | membrane