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QuickView for NT5E (gene)

Gene Symbol:
NT5E Homo sapiens Homo sapiens
Full name:
5'-nucleotidase ecto
CALJA, CD73, E5NT, NT, NT5, NTE, eN, eNT, 5'-nucleotidase, 5'-NT, Purine 5-Prime-Nucleotidase, ecto-5'-nucleotidase
Genomic Location:
Chr 6: 86216528-86262215
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different ...
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 6

Transcripts Names
Protein Names

GO Molecular Function

nucleotidase activity | cation binding | nucleotide binding | phosphatase activity | hydrolase activity | catalytic activity | hydrolase activity, acting on ester bonds | ion binding | organic cyclic compound binding | phosphoric ester hydrolase activity | 5'-nucleotidase activity | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

purine ribonucleotide metabolic process | nucleoside phosphate catabolic process | pyrimidine nucleoside metabolic process | organophosphate catabolic process | nucleoside catabolic process | nucleotidase activity | cellular process | organic substance catabolic process | negative regulation of inflammatory response | nucleotide metabolic process | carbohydrate derivative catabolic process | ribose phosphate metabolic process | ribonucleotide metabolic process | adenosine metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | phosphatase activity | purine nucleotide metabolic process | AMP catabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | cofactor metabolic process | cellular biosynthetic process | purine nucleoside metabolic process | nucleobase-containing compound catabolic process | purine nucleoside monophosphate catabolic process | drug catabolic process | nitrogen compound metabolic process | phosphorus metabolic process | organophosphate metabolic process | nucleoside metabolic process | nucleobase-containing small molecule catabolic process | adenosine biosynthetic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | biosynthetic process | aromatic compound biosynthetic process | nucleotide catabolic process | phosphate-containing compound metabolic process | aromatic compound catabolic process | drug metabolic process | AMP metabolic process | DNA metabolic process | leukocyte cell-cell adhesion | metabolic process | cell adhesion | nucleobase-containing compound metabolic process | organic substance metabolic process | cell-cell adhesion | organonitrogen compound catabolic process | dephosphorylation | 5'-nucleotidase activity | nicotinamide nucleotide metabolic process | NAD metabolic process | carbohydrate derivative metabolic process | heterocycle metabolic process | purine ribonucleotide catabolic process | cellular metabolic process | regulation of inflammatory response | purine nucleotide catabolic process | macromolecule metabolic process | pyrimidine nucleoside catabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | intrinsic component of membrane | cytoplasm | intracellular organelle | nucleoplasm | plasma membrane | vesicle | extracellular exosome | anchored component of membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | cell periphery | membrane-enclosed lumen | cytosol | cell surface | intracellular | membrane