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QuickView for NTN1 (gene)


Gene Symbol:
NTN1 Homo sapiens Homo sapiens
Full name:
netrin 1
Synonyms:
NTN1L, netrin-1, epididymis tissue protein Li 131P, netrin 1, mouse, homolog of
Genomic Location:
Chr 17: 8865584-9088042
Description:
Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 17
17p13.1


Transcripts Names
NM_004822
XM_006721595
Protein Names
O95631
E9KL51



GO Molecular Function

protein binding

GO Biological Process

cell morphogenesis | inner ear morphogenesis | positive regulation of locomotion | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | negative regulation of netrin-activated signaling pathway | intracellular signal transduction | regulation of cell development | regulation of localization | mammary gland duct morphogenesis | morphogenesis of an epithelium | establishment of localization | neuron migration | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | nervous system development | cell part morphogenesis | positive regulation of axonogenesis | neurogenesis | positive regulation of cellular component movement | generation of neurons | intracellular transport | cellular process | negative regulation of axonogenesis | establishment of organelle localization | regulation of cell motility | localization | cell projection morphogenesis | epithelial tube morphogenesis | negative regulation of signaling | neuron development | negative regulation of developmental growth | axon guidance | regulation of neuron projection development | establishment of localization in cell | tissue development | regulation of cell differentiation | regulation of cellular process | positive regulation of cell growth | organelle localization | small GTPase mediated signal transduction | epithelium development | cellular component organization | negative regulation of cell morphogenesis involved in differentiation | mammary gland morphogenesis | response to stimulus | cell morphogenesis involved in neuron differentiation | gland morphogenesis | neuron projection guidance | regulation of cell proliferation | negative regulation of neuron projection development | tube morphogenesis | programmed cell death | cellular localization | regulation of cellular component size | cellular component assembly | regulation of axon extension | embryo development | Cdc42 protein signal transduction | locomotion | apoptotic process | system development | regulation of signal transduction | negative regulation of growth | positive regulation of neuron projection development | multicellular organism development | cell migration | mammary gland development | regulation of axonogenesis | anterior/posterior axon guidance | regulation of neuron differentiation | axon development | cell projection assembly | animal organ morphogenesis | regulation of cell migration | positive regulation of cell projection organization | regulation of cellular component movement | axonogenesis | positive regulation of cell differentiation | cell morphogenesis involved in differentiation | sensory organ development | nuclear migration | cell communication | inner ear development | positive regulation of cell proliferation | regulation of locomotion | negative regulation of cell growth | embryonic morphogenesis | positive regulation of axon extension | nucleus localization | neuron differentiation | embryonic organ morphogenesis | regulation of cell morphogenesis involved in differentiation | regulation of growth | gland development | negative regulation of cell projection organization | tissue morphogenesis | Rho protein signal transduction | substrate-dependent cell migration | anatomical structure development | positive regulation of neurogenesis | cell projection organization | positive regulation of cell development | embryonic organ development | ear development | negative regulation of axon extension | cell adhesion | neuron projection development | cell death | animal organ development | negative regulation of neuron differentiation | mammary gland epithelium development | cell-cell adhesion | regulation of cell communication | negative regulation of signal transduction | positive regulation of developmental growth | signaling | positive regulation of growth | cell development | regulation of developmental growth | regulation of cell size | anatomical structure morphogenesis | regulation of nervous system development | regulation of developmental process | developmental process | regulation of cell growth | tube development | Ras protein signal transduction | positive regulation of neuron differentiation | regulation of cell projection organization | positive regulation of cell motility | positive regulation of cell morphogenesis involved in differentiation | negative regulation of cell development | chemotaxis | ear morphogenesis | negative regulation of cell differentiation | regulation of cellular component organization | substrate-dependent cell migration, cell extension | signal transduction | regulation of signaling | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

extracellular matrix | basement membrane | cell | cytoplasm | collagen-containing extracellular matrix | extracellular region | intracellular