QuickView for NTRK2 (gene)

Gene Symbol:

NTRK2 Homo sapiens

Full name:

neurotrophic receptor tyrosine kinase 2

Synonyms:

GP145-TrkB, OBHD, TRKB, trk-B, BDNF/NT-3 growth factors receptor, BDNF-tropomyosine receptor kinase B, neurotrophic tyrosine kinase receptor type 2, tropomyosin-related kinase B, tyrosine kinase receptor B

Genomic Location:

Chr 9: 86473286-86828325

Description:

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disord...

View Full Description

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  PAX4_04 ,  SMTTTTGT_UNKNOWN ,  MYOD_01 ,  ACACTCC_MIR122A ,  ATF6_01 ,  AAAGGGA_MIR204_MIR211 ,  HOXA4_Q2 ,  AP3_Q6 ,  VDR_Q6 ,  FAC1_01 ,  GGGAGGRR_MAZ_Q6 ,  GGGYGTGNY_UNKNOWN ,  GTGACGY_E4F1_Q6 ,  CCTGTGA_MIR513 ,  GGATTA_PITX2_Q2 ,  RP58_01 ,  CAGGTG_E12_Q6 ,  AP1FJ_Q2 ,  PITX2_Q2 ,  NKX25_02 ,  TAATAAT_MIR126 ,  AAAGACA_MIR511 ,  GCM_Q2 ,  ACTGCAG_MIR173P ,  GGCAGCT_MIR22 ,  TTGTTT_FOXO4_01 ,  ATF1_Q6 ,  CHOP_01 ,  AAAYRNCTG_UNKNOWN ,  RTTTNNNYTGGM_UNKNOWN ,  WTTGKCTG_UNKNOWN ,  GTTATAT_MIR410 ,  CREB_Q2 ,  CTGCAGY_UNKNOWN ,  AP1_Q2 ,  PAX4_03 ,  TCATCTC_MIR143 ,  PAX2_02 ,  CEBPGAMMA_Q6 ,  CTGRYYYNATT_UNKNOWN ,  TAXCREB_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-143 ,  Predicted Gene Targets for miR-22 ,  Predicted Gene Targets for miR-299 ,  Predicted Gene Targets for miR-151 ,  Predicted Gene Targets for miR-544

Cytogenetic Map:

9q21.33

search → result