QuickView for NUR77 (gene)
- Gene Symbol:
- Nr4a1
Rattus norvegicus - Full name:
- nuclear receptor subfamily 4, group A, member 1
- Synonyms:
- HMR, Ngfi-b, Nur77, nuclear receptor subfamily 4 group A member 1, Orphan nuclear receptor HMR, immediate early gene transcription factor NGFI-B, nerve growth factor induced protein I-B
- Genomic Location:
- Chr 7: 140012807-140020590
- Description:
-
putative ligand-dependent transcriptional activator
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Canis lupus familiaris , Danio rerio , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- miRNA binding sites
(Source: miRecords):
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nuclear receptor activity | cation binding | hormone receptor binding | transcription factor activity, direct ligand regulated sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | signaling receptor binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | steroid hormone receptor activity | RNA polymerase II regulatory region DNA binding | DNA binding | signaling receptor activity | sequence-specific double-stranded DNA binding | identical protein binding | nuclear hormone receptor binding | protein heterodimerization activity | ion binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | protein homodimerization activity | zinc ion binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transition metal ion binding | steroid hormone receptor binding | metal ion binding | glucocorticoid receptor binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | regulation of cysteine-type endopeptidase activity | cell motility | muscle tissue development | positive regulation of apoptotic process | regulation of programmed cell death | negative regulation of cysteine-type endopeptidase activity | blood vessel endothelial cell migration | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cell differentiation | positive regulation of epithelial cell proliferation | epithelial cell migration | positive regulation of endothelial cell proliferation | hormone-mediated signaling pathway | negative regulation of proteolysis | blood vessel morphogenesis | positive regulation of cellular biosynthetic process | cellular process | nuclear receptor activity | localization | epithelium migration | transcription factor activity, direct ligand regulated sequence-specific DNA binding | negative regulation of apoptotic process | regulation of proteolysis | regulation of cell cycle | response to growth factor | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | response to peptide hormone | tissue development | muscle structure development | skeletal muscle organ development | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | sprouting angiogenesis | response to stimulus | vasculature development | cellular response to vascular endothelial growth factor stimulus | cellular response to fibroblast growth factor stimulus | endothelial cell migration | skeletal muscle tissue development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | response to peptide | programmed cell death | cardiovascular system development | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | steroid hormone receptor activity | steroid hormone mediated signaling pathway | cellular biosynthetic process | cell chemotaxis | blood vessel development | regulation of nucleic acid-templated transcription | locomotion | response to nitrogen compound | apoptotic process | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | multicellular organism development | negative regulation of catalytic activity | cell migration | cellular response to peptide hormone stimulus | regulation of peptidase activity | regulation of catalytic activity | negative regulation of peptidase activity | regulation of gene expression | response to lipid | cellular response to peptide | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of transcription by RNA polymerase II | fat cell differentiation | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | angiogenesis | striated muscle tissue development | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of cell proliferation | regulation of RNA metabolic process | cellular response to corticotropin-releasing hormone stimulus | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | endothelial cell chemotaxis | DNA-binding transcription factor activity | response to organic substance | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | positive regulation of cell death | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | cell death | animal organ development | regulation of endothelial cell proliferation | negative regulation of cellular protein metabolic process | gene expression | positive regulation of programmed cell death | response to corticotropin-releasing hormone | cellular response to steroid hormone stimulus | transcription, DNA-templated | intracellular receptor signaling pathway | anatomical structure formation involved in morphogenesis | negative regulation of cell cycle | negative regulation of protein metabolic process | negative regulation of molecular function | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | regulation of epithelial cell proliferation | anatomical structure morphogenesis | regulation of endopeptidase activity | cellular macromolecule biosynthetic process | developmental process | tube development | positive regulation of transcription, DNA-templated | cell migration involved in sprouting angiogenesis | response to fibroblast growth factor | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | negative regulation of hydrolase activity | positive regulation of metabolic process | regulation of type B pancreatic cell proliferation | cellular metabolic process | ameboidal-type cell migration | cellular response to organic substance | regulation of cell death | response to steroid hormone | negative regulation of cell death | circulatory system development | chemotaxis | skeletal muscle cell differentiation | muscle organ development | signal transduction | negative regulation of endopeptidase activity | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | cell | transcription factor complex | cytoplasm | intracellular organelle | protein-containing complex | endomembrane system | nuclear envelope | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular | membrane
