QuickView for NaV1 (gene)

Gene Symbol:

NAV1 Homo sapiens

Full name:

neuron navigator 1

Synonyms:

POMFIL3, STEERIN1, UNC53H1, neuron navigator 1, pore membrane and/or filament interacting like protein 3, unc-53 homolog 1

Genomic Location:

Chr 1: 199884073-200061078

Description:

This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The e...

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This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACTGCC_MIR34A_MIR34C_MIR449 ,  PU1_Q6 ,  GAGCCTG_MIR484 ,  TTTTGAG_MIR373 ,  SRF_Q6 ,  CATTGTYY_SOX9_B1 ,  SOX9_B1 ,  LEF1_Q2 ,  GCACCTT_MIR18A_MIR18B ,  RP58_01 ,  GAGCTGG_MIR337 ,  TGCCTTA_MIR124A ,  ACTGCCT_MIR34B ,  GAANYNYGACNY_UNKNOWN ,  RORA1_01 ,  GTGCCTT_MIR506 ,  ATATGCA_MIR448 ,  RGAGGAARY_PU1_Q6 ,  TCCATTKW_UNKNOWN ,  CAGCTG_AP4_Q5 ,  SP1_Q6_01 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  ERR1_Q2 ,  SF1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-18 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-34 ,  Predicted Gene Targets for miR-34b ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-503 ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-542-3p ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-29 ,  Predicted Gene Targets for miR-544

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Cytogenetic Map:

1q32.1

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