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QuickView for Neu2 (gene)


Gene Symbol:
NEU2 Homo sapiens Homo sapiens
Full name:
neuraminidase 2
Synonyms:
SIAL2, sialidase-2, N-acetyl-alpha-neuraminidase 2, cytosolic sialidase, sialidase 2 (cytosolic sialidase)
Genomic Location:
Chr 2: 233605626-233608011
Description:
This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 2
2q37.1


Transcripts Names
NM_005383
Protein Names
Q9Y3R4
Q3KNW4
Q6NTB4



GO Molecular Function

hydrolase activity | hydrolase activity, hydrolyzing O-glycosyl compounds | exo-alpha-(2->6)-sialidase activity | exo-alpha-sialidase activity | catalytic activity | hydrolase activity, acting on glycosyl bonds | protein binding | exo-alpha-(2->3)-sialidase activity | alpha-sialidase activity | exo-alpha-(2->8)-sialidase activity

GO Biological Process

glycosphingolipid metabolic process | glycolipid catabolic process | cellular process | organic substance catabolic process | ganglioside metabolic process | carbohydrate derivative catabolic process | sphingolipid metabolic process | carbohydrate catabolic process | catabolic process | ceramide catabolic process | cellular lipid metabolic process | ceramide metabolic process | cellular nitrogen compound metabolic process | nitrogen compound metabolic process | lipid metabolic process | cellular carbohydrate metabolic process | cellular carbohydrate catabolic process | glycosphingolipid catabolic process | cellular amide metabolic process | glycolipid metabolic process | carbohydrate metabolic process | membrane lipid catabolic process | ganglioside catabolic process | cellular lipid catabolic process | oligosaccharide metabolic process | metabolic process | membrane lipid metabolic process | lipid catabolic process | organic substance metabolic process | organonitrogen compound catabolic process | cellular oligosaccharide catabolic process | carbohydrate derivative metabolic process | sphingolipid catabolic process | cellular oligosaccharide metabolic process | cellular metabolic process | oligosaccharide catabolic process

GO Cellular Component

intracellular membrane-bounded organelle | catalytic complex | cell | cytoplasm | intracellular organelle | protein-containing complex | membrane-bounded organelle | organelle | cytosol | intracellular