QuickView for Neurokinin 1 (gene)

Gene Symbol:

TAC1 Homo sapiens

Full name:

tachykinin precursor 1

Synonyms:

Hs.2563, NK2, NKNA, NPK, TAC2, protachykinin-1, PPT, neurokinin 1, neurokinin 2, neurokinin A, neurokinin alpha, neuromedin L, neuropeptide K, neuropeptide gamma, preprotachykinin, protachykinin, substance K, substance P, tachykinin 2, tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)

Genomic Location:

Chr 7: 97199311-97207720

Description:

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and fun...

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This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  TGANTCA_AP1_C ,  TAL1ALPHAE47_01 ,  USF_Q6 ,  TTANTCA_UNKNOWN ,  ARNT_01 ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  YATTNATC_UNKNOWN ,  WHN_B ,  GGGAGGRR_MAZ_Q6 ,  CDP_01 ,  CEBP_Q2 ,  CEBPDELTA_Q6 ,  TAL1BETAE47_01 ,  RP58_01 ,  CAGGTG_E12_Q6 ,  AP1_01 ,  LHX3_01 ,  HNF3B_01 ,  CEBPB_02 ,  ATGTTTC_MIR494 ,  GTGCCAA_MIR96 ,  AP1_Q2_01 ,  S8_01 ,  HLF_01 ,  BACH1_01 ,  USF_Q6_01 ,  TAATTA_CHX10_01 ,  TAL1BETAITF2_01 ,  RNTCANNRNNYNATTW_UNKNOWN ,  AACTTT_UNKNOWN ,  USF_02 ,  AAGCACA_MIR218 ,  TCF11MAFG_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-494 ,  Predicted Gene Targets for miR-96

miRNA binding sites
(Source: miRecords):

hsa-miR-206 Targeted Genes ,  [miR-130a] Targeted Genes

Cytogenetic Map:

7q21.3

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