QuickView for Nup62 (gene)
- Gene Symbol:
- NUP62
Homo sapiens - Full name:
- nucleoporin 62
- Synonyms:
- IBSN, SNDI, p62, nuclear pore glycoprotein p62, 62 kDa nucleoporin, nucleoporin 62kD, nucleoporin 62kDa, nucleoporin Nup62
- Genomic Location:
- Chr 19: 55101894-55124598
- Description:
-
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nu...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Saccharomyces cerevisiae , Bos taurus , Schizosaccharomyces pombe , Gallus gallus , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
19q13.33
GO Molecular Function
structural molecule activity | receptor signaling complex scaffold activity | hormone receptor binding | PTB domain binding | lipid binding | signaling receptor binding | thyroid hormone receptor binding | structural constituent of nuclear pore | phospholipid binding | ubiquitin binding | chromatin binding | protein domain specific binding | Hsp70 protein binding | cytoskeletal protein binding | anion binding | kinesin binding | nuclear hormone receptor binding | ubiquitin-like protein binding | ion binding | protein binding | transcription factor binding | protein-containing complex scaffold activity | Hsp90 protein binding | heat shock protein binding | SH2 domain binding
GO Biological Process
RNA metabolic process | negative regulation of phosphorylation | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | regulation of intracellular protein transport | negative regulation of MAPK cascade | positive regulation of cellular component organization | regulation of cellular localization | nuclear export | regulation of localization | regulation of programmed cell death | establishment of localization | response to hormone | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | microtubule cytoskeleton organization | regulation of protein import | male gamete generation | negative regulation of protein phosphorylation | regulation of organelle organization | intracellular transport | hormone-mediated signaling pathway | microtubule-based process | positive regulation of cellular biosynthetic process | cellular process | regulation of centriole replication | establishment of organelle localization | centrosome separation | localization | protein transport | negative regulation of signaling | regulation of mitotic nuclear division | multicellular organismal reproductive process | protein heterotrimerization | macromolecule localization | negative regulation of apoptotic process | microtubule organizing center organization | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | positive regulation of cell division | regulation of mitotic spindle organization | establishment of localization in cell | negative regulation of cellular metabolic process | gamete generation | interspecies interaction between organisms | positive regulation of cytokinesis | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | regulation of mitotic cytokinetic process | organelle localization | protein import into nucleus | regulation of protein localization to centrosome | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | negative regulation of epidermal growth factor receptor signaling pathway | cellular component organization | establishment of chromosome localization | regulation of cell division | protein export from nucleus | response to stimulus | regulation of cellular protein localization | regulation of centrosome cycle | chromosome segregation | intracellular protein transport | negative regulation of protein kinase activity | positive regulation of cellular protein localization | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | protein localization to nucleus | structural constituent of nuclear pore | reproduction | cellular localization | cellular nitrogen compound metabolic process | regulation of protein transport | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | positive regulation of centriole replication | regulation of peptide transport | cellular biosynthetic process | positive regulation of ERBB signaling pathway | regulation of intracellular transport | mRNA export from nucleus | regulation of nucleic acid-templated transcription | organelle assembly | cellular response to hormone stimulus | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of organelle organization | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of MAPK cascade | sister chromatid segregation | ribonucleoprotein complex localization | positive regulation of organelle assembly | protein complex oligomerization | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of mitotic cytokinesis | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of small GTPase mediated signal transduction | regulation of gene expression | organic substance transport | positive regulation of centrosome duplication | cell cycle | positive regulation of cellular metabolic process | mitotic metaphase plate congression | regulation of protein localization to nucleus | regulation of nitrogen compound metabolic process | peptide transport | positive regulation of intracellular signal transduction | negative regulation of protein serine/threonine kinase activity | protein localization to organelle | import into nucleus | biosynthetic process | metaphase plate congression | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | RNA export from nucleus | mRNA transport | establishment of RNA localization | mitotic centrosome separation | protein import | nuclear chromosome segregation | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of cytokinesis | protein trimerization | protein-containing complex localization | positive regulation of cytoskeleton organization | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | negative regulation of MAP kinase activity | regulation of RNA metabolic process | viral process | cell aging | regulation of mitotic cell cycle | regulation of microtubule-based process | regulation of nucleocytoplasmic transport | multicellular organism reproduction | regulation of centrosome duplication | protein-containing complex assembly | regulation of establishment of protein localization | response to organic substance | regulation of protein import into nucleus | centrosome cycle | regulation of kinase activity | centriole assembly | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | establishment of protein localization to organelle | nucleobase-containing compound transport | mitotic cell cycle | cell surface receptor signaling pathway | nuclear division | metabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | cellular protein localization | amide transport | nucleobase-containing compound metabolic process | negative regulation of ERBB signaling pathway | positive regulation of cellular component biogenesis | organic substance metabolic process | regulation of epidermal growth factor receptor signaling pathway | nuclear transport | cell death | negative regulation of cellular protein metabolic process | gene expression | negative regulation of small GTPase mediated signal transduction | negative regulation of Ras protein signal transduction | regulation of phosphate metabolic process | cytoskeleton organization | mitotic nuclear division | establishment of protein localization | transcription, DNA-templated | RNA transport | negative regulation of protein metabolic process | positive regulation of mitotic cytokinetic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | regulation of transcription, DNA-templated | regulation of ERBB signaling pathway | protein localization | positive regulation of epidermal growth factor receptor signaling pathway | regulation of Ras protein signal transduction | protein heterooligomerization | positive regulation of protein localization to centrosome | cellular macromolecule localization | cellular macromolecule biosynthetic process | nucleocytoplasmic transport | developmental process | organelle organization | positive regulation of cell cycle process | spermatogenesis | regulation of transport | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of mitotic cytokinesis | positive regulation of nucleic acid-templated transcription | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | cellular metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | regulation of organelle assembly | negative regulation of cell death | aging | mitotic sister chromatid segregation | RNA localization | sexual reproduction | regulation of microtubule cytoskeleton organization | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of cellular component organization | regulation of cytoskeleton organization | positive regulation of signaling | positive regulation of mitotic nuclear division | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | microtubule organizing center | nuclear membrane | cell | annulate lamellae | cytoplasm | spindle | intracellular organelle | centrosome | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | nuclear envelope | midbody | ribonucleoprotein complex | microtubule cytoskeleton | spindle pole | membrane-bounded organelle | nucleus | organelle | Flemming body | nuclear pore | cytoskeleton | intracellular | mitotic spindle | membrane | nuclear pore central transport channel
