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QuickView for Nup98 (gene)


Gene Symbol:
NUP98 Homo sapiens Homo sapiens
Full name:
nucleoporin 98
Synonyms:
ADIR2, NUP196, NUP96, nuclear pore complex protein Nup98-Nup96, nuclear pore complex protein Nup98, GLFG-repeat containing nucleoporin, NUP98/PHF23 fusion 2 protein, Nup98-Nup96, nucleoporin 98kD, nucleoporin 98kDa
Genomic Location:
Chr 11: 3652816-3775468
Description:
Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 11
11p15.4





GO Molecular Function

structural molecule activity | nuclear localization sequence binding | peptide binding | nucleic acid binding | mRNA binding | signal sequence binding | hydrolase activity | structural constituent of nuclear pore | catalytic activity | chromatin binding | serine hydrolase activity | amide binding | transporter activity | promoter-specific chromatin binding | organic cyclic compound binding | transcription coactivator activity | protein binding | serine-type peptidase activity | transcription coregulator activity | heterocyclic compound binding | peptidase activity | RNA binding

GO Biological Process

nucleus organization | positive regulation of macromolecule biosynthetic process | nuclear export | proteolysis | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery | establishment of localization | nuclear pore complex assembly | intracellular transport | regulation of mRNA processing | positive regulation of cellular biosynthetic process | cellular process | localization | protein transport | macromolecule localization | positive regulation of nitrogen compound metabolic process | establishment of localization in cell | interspecies interaction between organisms | regulation of cellular process | regulation of metabolic process | organelle localization | regulation of mRNA splicing, via spliceosome | protein import into nucleus | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | protein export from nucleus | intracellular protein transport | positive regulation of RNA splicing | protein localization to nucleus | structural constituent of nuclear pore | cellular localization | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | positive regulation of mRNA processing | cellular biosynthetic process | mRNA export from nucleus | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | telomere localization | ribonucleoprotein complex localization | regulation of gene expression | organic substance transport | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | peptide transport | protein localization to organelle | import into nucleus | biosynthetic process | RNA export from nucleus | mRNA transport | cellular protein-containing complex assembly | establishment of RNA localization | pore complex assembly | protein import | regulation of cellular metabolic process | protein-containing complex localization | transcription coactivator activity | regulation of RNA metabolic process | viral process | positive regulation of mRNA splicing, via spliceosome | protein-containing complex assembly | protein metabolic process | telomere tethering at nuclear periphery | DNA metabolic process | nuclear pore organization | establishment of protein localization to organelle | nucleobase-containing compound transport | metabolic process | regulation of RNA splicing | regulation of RNA biosynthetic process | cellular protein localization | amide transport | nucleobase-containing compound metabolic process | organic substance metabolic process | nuclear transport | gene expression | serine-type peptidase activity | establishment of protein localization | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery | RNA transport | protein localization | cellular macromolecule localization | cellular macromolecule biosynthetic process | nucleocytoplasmic transport | organelle organization | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | cellular metabolic process | peptidase activity | DNA replication | RNA localization | positive regulation of gene expression | macromolecule metabolic process

GO Cellular Component

nuclear inclusion body | chromosome | intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | chromosome, centromeric region | cell | nuclear lumen | kinetochore | cytoplasm | intracellular organelle | nuclear body | inclusion body | protein-containing complex | endomembrane system | nucleoplasm | nuclear envelope | ribonucleoprotein complex | nuclear pore outer ring | membrane-bounded organelle | nucleus | organelle | nuclear pore cytoplasmic filaments | membrane-enclosed lumen | nuclear pore nuclear basket | nuclear pore | cytosol | intracellular | membrane | nuclear periphery