QuickView for OAT3 (gene)

Gene Symbol:

SLC22A8 Homo sapiens

Full name:

solute carrier family 22 member 8

Synonyms:

OAT3, solute carrier family 22 member 8, hOAT3, organic anion transporter 3, solute carrier family 22 (organic anion transporter), member 8

Genomic Location:

Chr 11: 62516872-62539887

Description:

This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein iso...

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This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

POU6F1_01 ,  TGGNNNNNNKCCAR_UNKNOWN ,  EFC_Q6 ,  HNF1_C ,  CTTTGA_LEF1_Q2 ,  TTAYRTAA_E4BP4_01 ,  TCF4_Q5 ,  LEF1_Q6 ,  LEF1_Q2 ,  CAGGTG_E12_Q6 ,  MEIS1_01 ,  AHR_01 ,  TTGTTT_FOXO4_01 ,  CEBP_C ,  WWTAAGGC_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  RYTAAWNNNTGAY_UNKNOWN

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Cytogenetic Map:

11q12.3

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