Correlation Engine 2.0
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QuickView for ODC1 (gene)


Gene Symbol:
ODC1 Homo sapiens Homo sapiens
Full name:
ornithine decarboxylase 1
Synonyms:
ODC, ornithine decarboxylase
Genomic Location:
Chr 2: 10497959-10505904
Description:
This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding th...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Danio rerio Schizosaccharomyces pombe Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 2
2p25.1





GO Molecular Function

lyase activity | carbon-carbon lyase activity | catalytic activity | identical protein binding | carboxy-lyase activity | ornithine decarboxylase activity | protein binding | protein homodimerization activity | protein dimerization activity

GO Biological Process

response to virus | cellular process | cellular amino acid metabolic process | cellular biogenic amine metabolic process | regulation of cellular process | regulation of metabolic process | urogenital system development | response to stimulus | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | cellular nitrogen compound metabolic process | polyamine metabolic process | amine metabolic process | cellular biosynthetic process | kidney development | response to external biotic stimulus | system development | nitrogen compound metabolic process | multicellular organism development | regulation of cellular amino acid metabolic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | putrescine biosynthetic process from ornithine | biosynthetic process | regulation of cellular metabolic process | regulation of protein metabolic process | polyamine biosynthetic process | positive regulation of cell proliferation | renal system development | carboxylic acid metabolic process | anatomical structure development | metabolic process | ornithine metabolic process | regulation of protein catabolic process | organic substance metabolic process | animal organ development | amine biosynthetic process | organic acid metabolic process | response to biotic stimulus | regulation of cellular ketone metabolic process | developmental process | putrescine biosynthetic process | cellular metabolic process | response to other organism | multicellular organismal process

GO Cellular Component

cell | cytoplasm | perinuclear region of cytoplasm | cytosol | intracellular