QuickView for OSBPL9 (gene)

Gene Symbol:

OSBPL9 Homo sapiens

Full name:

oxysterol binding protein like 9

Synonyms:

ORP-9, ORP9, oxysterol-binding protein-related protein 9, OSBP-related protein 9

Genomic Location:

Chr 1: 51855352-52026729

Description:

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a choleste...

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This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  SP1_01 ,  CREBP1CJUN_01 ,  TGGNNNNNNKCCAR_UNKNOWN ,  CREB_Q4 ,  E2F1_Q4 ,  TGAYRTCA_ATF3_Q6 ,  ATF_B ,  CREBP1_Q2 ,  CAGGTG_E12_Q6 ,  CTCAGGG_MIR125B_MIR125A ,  SP1_Q4_01 ,  RRAGTTGT_UNKNOWN ,  NFY_Q6 ,  CTTTAAR_UNKNOWN ,  SP1_Q6 ,  ATF1_Q6 ,  CREB_Q2 ,  TGACGTCA_ATF3_Q6 ,  PAX_Q6 ,  AACTTT_UNKNOWN ,  YNGTTNNNATT_UNKNOWN ,  CEBPGAMMA_Q6 ,  CREB_01 ,  SP1_Q2_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-188

Cytogenetic Map:

1p32.3

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