QuickView for Olig2 (gene)

Gene Symbol:

OLIG2 Homo sapiens

Full name:

oligodendrocyte transcription factor 2

Synonyms:

BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19, oligodendrocyte transcription factor 2, basic domain, helix-loop-helix protein, class B, 1, class B basic helix-loop-helix protein 1, class E basic helix-loop-helix protein 19, human protein kinase C-binding protein RACK17, oligodendrocyte lineage transcription factor 2, oligodendrocyte-specific bHLH transcription factor 2, protein kinase C-binding protein 2

Genomic Location:

Chr 21: 33320109-33323370

Description:

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosoma...

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This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SP1_01 ,  CATTGTYY_SOX9_B1 ,  AAANWWTGC_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  TGAYRTCA_ATF3_Q6 ,  TATAAA_TATA_01 ,  DBP_Q6 ,  ALPHACP1_01 ,  TST1_01 ,  TATA_C ,  ATF3_Q6 ,  GGGCGGR_SP1_Q6 ,  NFY_01 ,  TATA_01 ,  TGACAGNY_MEIS1_01 ,  GCTNWTTGK_UNKNOWN ,  TGACATY_UNKNOWN

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Cytogenetic Map:

21q22.11

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