QuickView for Optineurin (gene)

GO Molecular Function

K63-linked polyubiquitin modification-dependent protein binding | GTPase binding | cation binding | enzyme binding | ubiquitin binding | Ras GTPase binding | polyubiquitin modification-dependent protein binding | protein binding, bridging | modification-dependent protein binding | identical protein binding | ubiquitin-like protein binding | ion binding | TFIIIA-class transcription factor binding | molecular adaptor activity | protein binding | transcription factor binding | small GTPase binding | Rab GTPase binding | metal ion binding | protein C-terminus binding

GO Biological Process

protein homooligomerization | positive regulation of cellular component organization | protein localization to cell periphery | positive regulation of apoptotic process | regulation of programmed cell death | defense response to other organism | establishment of localization | regulation of autophagy | negative regulation of neuron death | negative regulation of cellular process | defense response | regulation of organelle organization | defense response to Gram-negative bacterium | regulation of neuron death | cellular process | secretion | localization | protein transport | negative regulation of signaling | parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization | macromolecule localization | negative regulation of apoptotic process | endomembrane system organization | negative regulation of cellular metabolic process | Golgi to plasma membrane transport | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | cellular response to unfolded protein | response to topologically incorrect protein | cellular component organization | cellular response to topologically incorrect protein | positive regulation of autophagy of mitochondrion | response to stimulus | response to stress | establishment of protein localization to plasma membrane | regulation of cell proliferation | negative regulation of receptor recycling | cellular localization | secretion by cell | positive regulation of mitophagy in response to mitochondrial depolarization | regulation of macroautophagy | negative regulation of metabolic process | cellular component assembly | positive regulation of mitochondrion organization | negative regulation of neuron apoptotic process | response to external biotic stimulus | regulation of signal transduction | positive regulation of organelle organization | protein complex oligomerization | protein localization to plasma membrane | post-Golgi vesicle-mediated transport | regulation of gene expression | protein localization to membrane | organic substance transport | cellular response to stress | positive regulation of cellular metabolic process | positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization | peptide transport | vesicle-mediated transport | Golgi ribbon formation | protein localization to organelle | positive regulation of neuron death | autophagy | regulation of mitochondrion organization | response to bacterium | peptide secretion | regulation of cellular metabolic process | regulation of neuron apoptotic process | defense response to bacterium | positive regulation of cell proliferation | Golgi vesicle transport | regulation of autophagy of mitochondrion | establishment of protein localization to membrane | cytokine production | protein-containing complex assembly | protein localization to Golgi apparatus | response to organic substance | Golgi organization | positive regulation of xenophagy | Golgi to plasma membrane protein transport | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | positive regulation of neuron apoptotic process | regulation of neural precursor cell proliferation | metabolic process | cytokine secretion | negative regulation of I-kappaB kinase/NF-kappaB signaling | negative regulation of programmed cell death | cellular protein localization | amide transport | positive regulation of cell death | immune response | positive regulation of programmed cell death | positive regulation of autophagy | establishment of protein localization | positive regulation of cytokine production | positive regulation of macroautophagy | regulation of cell communication | response to mitochondrial depolarisation | negative regulation of signal transduction | protein localization | response to unfolded protein | regulation of cytokine production | cellular macromolecule localization | response to biotic stimulus | positive regulation of neural precursor cell proliferation | organelle organization | positive regulation of mitophagy | negative regulation of cell proliferation | regulation of receptor recycling | innate immune response | positive regulation of metabolic process | immune system process | cellular metabolic process | cellular response to organic substance | regulation of cell death | protein secretion | negative regulation of cell death | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of cellular component organization | response to other organism | regulation of signaling | positive regulation of gene expression | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | neuronal cell body | cytoplasm | intracellular organelle | Golgi apparatus | cell projection | endomembrane system | vesicle | perinuclear region of cytoplasm | endosome | membrane-bounded organelle | nucleus | organelle | axon | trans-Golgi network | cytosol | intracellular vesicle | intracellular

PATHWAYS

No pathways found.

PROTEIN FAMILY

NF-kappa-B essential modulator NEMO, N-terminal | NF-kappa-B essential modulator NEMO, CC2-LZ domain | Optineurin | NEMO, Zinc finger