QuickView for Osc (gene)
- Gene Symbol:
- LSS
Homo sapiens - Full name:
- lanosterol synthase
- Synonyms:
- CTRCT44, OSC, lanosterol synthase, 2,3-epoxysqualene-lanosterol cyclase, hOSC, lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase), oxidosqualene--lanosterol cyclase
- Genomic Location:
- Chr 21: 46432788-46473119
- Description:
-
The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isofo...
- Orthologs:
- Mus musculus , Rattus norvegicus , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
21q22.3
GO Molecular Function
isomerase activity | lanosterol synthase activity | catalytic activity | intramolecular transferase activity
GO Biological Process
sterol metabolic process | regulation of metabolic process | organic cyclic compound metabolic process | steroid biosynthetic process | alcohol metabolic process | regulation of steroid biosynthetic process | regulation of steroid metabolic process | organic hydroxy compound metabolic process | regulation of protein stability | lipid metabolic process | regulation of cholesterol biosynthetic process | sterol biosynthetic process | small molecule metabolic process | regulation of cholesterol metabolic process | biosynthetic process | cholesterol biosynthetic process | lipid biosynthetic process | regulation of lipid biosynthetic process | metabolic process | cholesterol metabolic process | organic substance metabolic process | steroid metabolic process | regulation of lipid metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | lipid droplet | membrane-bounded organelle | organelle | intracellular | membrane
