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QuickView for Oxyphencyclimine (compound)


PubChem
Name: oxyphencyclimine
PubChem Compound ID: 4642
Molecular formula: C20H28N2O3
Molecular weight: 344.448 g/mol
Synonyms:
Oxyphencyclimine; Cyclohexaneglycolic acid, .alpha.-phenyl-, (1,4,5, 6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester monohydrochloride; Benzeneacetic acid, .alpha.-cyclohexyl-.alpha.-hydroxy-, (1,4,5, 6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester, monohydrochloride; component of Enarax; KBioSS_002086; Oxyphencyclimine hydrochloride; KBioGR_000927; KBio1_000876; Cycmin; Daricol.
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DrugBank
Identification
Name: oxyphencyclimine
Name (isomeric): DB00383
Drug Type: small molecule
Synonyms:
Oxifencicliminum [INN-Spanish]; Oxyphencyclimine Hydrochloride; Oxiphencycliminum; Oxyphencycliminum [INN-Latin]
Brand: Zamanil, Gastrix, Setrol, W-T Anticholinergic, Cycmin, Ulcociclinina, Spazamin, Manir, Daricol, Vio-Thene, Antulcus, Dominil, Daricon, Caridan, Enterex, Naridan, Oximin, Syklifen
Category: Anticholinergic Agents, Antispasmodics
CAS number: 125-53-1
Pharmacology
Indication: For the treatment of peptic ulcer disease and the relief of smooth muscle spasms in gastrointestinal disorders.
Pharmacology: Oxyphencyclimine is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. Oxyphencyclimine is an antimuscarinic, anticholinergic drug.
Mechanism of Action:
Oxyphencyclimine binds the muscarinic acetylcholine receptor. It may block all three types of muscarinic receptors including M-1 receptors in the CNS and ganglia, M-2 receptors in the heart (vagus) and M-3 receptors at the parasympathetic NEJ system. The muscarinic acetylcholine receptors mediate various cellular responses, including inhibition of ...
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Affected organisms: Humans and other mammals
Interactions
Drug interaction:
HaloperidolThe anticholinergic increases the risk of psychosis and tardive dyskinesia

Targets