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QuickView for Oxytocin (compound)
PubChem
| Name: | Oxytocin |
|---|---|
| PubChem Compound ID: | 439302 |
| Description: | A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION. |
| Molecular formula: | C43H66N12O12S2 |
| Molecular weight: | 1007.19 g/mol |
| Synonyms: |
Pitocin; Pitocin (TN); Oxytocin; Oxytocin (TN); OT; Syntocinon (TN); D00089; OXT; Syntocinon; 50-56-6.
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DrugBank
Identification
| Name: | Oxytocin |
|---|---|
| Name (isomeric): | DB00107 |
| Drug Type: | biotech |
| Description: | A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION. |
| Synonyms: |
Pitocin; Syntocinon
|
| Brand: | Pitocin (Parke-Davis), Oxytocin (BAM Biotech), Syntocinon (Sandoz) |
| Category: | Oxytocics, Anti-tocolytic Agents, Labor Induction Agents |
| CAS number: | 50-56-6 |
Pharmacology
| Indication: | To assist in labor, elective labor induction, uterine contraction induction |
|---|---|
| Pharmacology: |
Used to induce labor or to enhance uterine contractions during labor. Uterine motility depends on the formation of the contractile protein actomyosin under the influence of the Ca2+-dependent phosphorylating enzyme myosin light-chain kinase. Oxytocin promotes contractions by increasing the intracellular Ca2+, which in turn activates myosins light c...
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| Mechanism of Action: | Binds the oxytocin receptor which leads to an increase in intracellular calcium levels. The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of milk ejection. |
| Protein binding: | 30% |
| Biotransformation: | hepatic oxytocinases |
| Route of elimination: | Biliary and renal |
| Half Life: | 1-6 min |
| Affected organisms: | Humans and other mammals |
Interactions
| Drug interaction: |
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Targets
Enzymes
