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QuickView for P2RY1 (gene)


Gene Symbol:
P2RY1 Homo sapiens Homo sapiens
Full name:
purinergic receptor P2Y1
Synonyms:
P2Y1, SARCC, P2Y purinoceptor 1, ATP receptor, P2 purinoceptor subtype Y1, platelet ADP receptor, purinergic receptor P2Y, G-protein coupled, 1, suppressing androgen receptor in renal cell carcinoma
Genomic Location:
Chr 3: 154035426-154038535
Description:
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mo...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3q25.2


Transcripts Names
NM_002563
Protein Names
P47900



GO Molecular Function

ADP binding | ADP-activated adenosine receptor activity | transmembrane signaling receptor activity | ribonucleotide binding | nucleotide binding | G-protein coupled purinergic nucleotide receptor activity | G-protein coupled receptor activity | signaling receptor binding | carbohydrate derivative binding | ATP-activated adenosine receptor activity | ATP binding | anion binding | adenyl nucleotide binding | signaling receptor activity | purine nucleotide binding | protein heterodimerization activity | scaffold protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | protein dimerization activity | G-protein coupled receptor binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | purinergic nucleotide receptor activity | A1 adenosine receptor binding | heterocyclic compound binding | G-protein coupled adenosine receptor activity | adenosine receptor binding | small molecule binding

GO Biological Process

signal transduction involved in regulation of gene expression | response to extracellular stimulus | regulation of ERK1 and ERK2 cascade | regulation of blood vessel diameter | positive regulation of macromolecule biosynthetic process | response to nutrient levels | response to ATP | cell motility | regulation of cell morphogenesis | protein localization to cell periphery | regulation of localization | regulation of carbohydrate metabolic process | regulation of cell shape | negative regulation of cellular process | cell differentiation | purinergic nucleotide receptor signaling pathway | nervous system development | cellular response to extracellular stimulus | response to drug | regulation of inositol phosphate biosynthetic process | cellular chemical homeostasis | neurogenesis | positive regulation of phosphate metabolic process | response to organophosphorus | positive regulation of cellular biosynthetic process | cellular process | regulation of catecholamine secretion | localization | cellular homeostasis | ADP-activated adenosine receptor activity | macromolecule localization | hemostasis | negative regulation of secretion | response to growth factor | positive regulation of nitrogen compound metabolic process | regulation of binding | regulation of cellular process | regulation of metabolic process | gliogenesis | regulation of cytosolic calcium ion concentration | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | calcium ion homeostasis | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | G-protein coupled purinergic nucleotide receptor activity | G-protein coupled receptor activity | response to stimulus | positive regulation of protein metabolic process | regulation of blood vessel size | regulation of norepinephrine secretion | response to stress | ATP-activated adenosine receptor activity | cellular localization | G-protein coupled purinergic nucleotide receptor signaling pathway | positive regulation of hormone secretion | negative regulation of transport | cellular response to organic cyclic compound | blood circulation | G-protein coupled receptor signaling pathway | positive regulation of RNA biosynthetic process | metal ion homeostasis | blood coagulation | regulation of nucleic acid-templated transcription | locomotion | response to nitrogen compound | system development | cellular response to nutrient levels | regulation of penile erection | regulation of signal transduction | negative regulation of secretion by cell | multicellular organism development | cell migration | regulation of MAPK cascade | response to purine-containing compound | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | relaxation of muscle | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | wound healing | protein localization to plasma membrane | regulation of gene expression | platelet activation | protein localization to membrane | cellular response to ATP | positive regulation of secretion | nervous system process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | glial cell migration | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | response to nutrient | negative regulation of norepinephrine secretion | negative regulation of binding | sensory perception of pain | regulation of cellular protein metabolic process | eating behavior | cation homeostasis | cellular response to drug | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | positive regulation of inositol phosphate biosynthetic process | regulation of protein metabolic process | positive regulation of signal transduction | cellular calcium ion homeostasis | homeostatic process | regulation of protein phosphorylation | regulation of RNA metabolic process | regulation of tube size | positive regulation of transport | coagulation | negative regulation of catecholamine secretion | regulation of signaling receptor activity | cellular response to nutrient | positive regulation of protein modification process | response to organic substance | cellular response to purine-containing compound | regulation of inositol trisphosphate biosynthetic process | response to wounding | response to mechanical stimulus | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | regulation of RNA biosynthetic process | regulation of body fluid levels | positive regulation of penile erection | regulation of tube diameter | cellular protein localization | chemical homeostasis | regulation of secretion | behavior | adenosine receptor signaling pathway | positive regulation of ion transport | positive regulation of ERK1 and ERK2 cascade | ion homeostasis | regulation of phosphate metabolic process | phospholipase C-activating G-protein coupled receptor signaling pathway | cell activation | positive regulation of MAPK cascade | sensory perception | positive regulation of carbohydrate metabolic process | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | negative regulation of molecular function | signaling | feeding behavior | regulation of transcription, DNA-templated | response to organic cyclic compound | protein localization | positive regulation of phosphorylation | cellular macromolecule localization | positive regulation of inositol trisphosphate biosynthetic process | regulation of developmental process | regulation of ion transport | developmental process | purinergic nucleotide receptor activity | regulation of transport | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | cellular metal ion homeostasis | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | G-protein coupled adenosine receptor activity | cellular response to organic substance | aging | divalent inorganic cation homeostasis | regulation of cellular component organization | muscle system process | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | dendrite | intracellular membrane-bounded organelle | synapse | apical plasma membrane | neuron projection | somatodendritic compartment | cell body | cell | intrinsic component of membrane | synaptic membrane | cytoplasm | intracellular organelle | dendritic tree | apical part of cell | cell projection | postsynaptic membrane | postsynapse | plasma membrane | postsynaptic density | asymmetric synapse | mitochondrion | integral component of plasma membrane | membrane-bounded organelle | organelle | postsynaptic specialization | cell periphery | basolateral plasma membrane | cell surface | intracellular | membrane | intrinsic component of plasma membrane