QuickView for P2RY2 (gene)

Gene Symbol:

P2RY2 Homo sapiens

Full name:

purinergic receptor P2Y2

Synonyms:

HP2U, P2RU1, P2U, P2U1, P2UR, P2Y2, P2Y2R, P2Y purinoceptor 2, ATP receptor, P2U nucleotide receptor, P2U purinoceptor 1, P2U receptor 1, purinergic receptor P2Y, G-protein coupled, 2, purinoceptor P2Y2

Genomic Location:

Chr 11: 72606992-72625045

Description:

The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine n...

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The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MYB_Q5_01 ,  E2F1_Q3_01 ,  MYB_Q6 ,  TTGTTT_FOXO4_01 ,  CTTTGT_LEF1_Q2 ,  MYB_Q3

Cytogenetic Map:

11q13.4

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