QuickView for P2X1 (gene)

Gene Symbol:

P2RX1 Homo sapiens

Full name:

purinergic receptor P2X 1

Synonyms:

P2X1, P2X purinoceptor 1, ATP receptor, P2X receptor, subunit 1, P2X1 receptor, purinergic receptor P2X, ligand gated ion channel, 1, purinergic receptor P2X1

Genomic Location:

Chr 17: 3746634-3766709

Description:

The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neuro...

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The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ZIC1_01 ,  ZIC3_01 ,  IK2_01 ,  IK1_01

Cytogenetic Map:

17p13.2

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