QuickView for P2X4 (gene)

Gene Symbol:

P2RX4 Homo sapiens

Full name:

purinergic receptor P2X 4

Synonyms:

P2X4, P2X4R, P2X purinoceptor 4, ATP receptor, ATP-gated cation channel protein, P2X receptor, subunit 4, purinergic receptor P2X, ligand gated ion channel, 4, purinergic receptor P2X4, purinoceptor P2X4

Genomic Location:

Chr 12: 120132047-120156292

Description:

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest s...

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The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  TGTYNNNNNRGCARM_UNKNOWN ,  TTGCCAA_MIR182 ,  CAGCTG_AP4_Q5 ,  LBP1_Q6

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-20

Cytogenetic Map:

12q24.31

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