QuickView for P2Y6 (gene)

Gene Symbol:

P2RY6 Homo sapiens

Full name:

pyrimidinergic receptor P2Y6

Synonyms:

P2Y6, P2Y purinoceptor 6, G-coupled nucleotide receptor, P2 purinoceptor, P2Y6 receptor, pyrimidinergic receptor P2Y, G-protein coupled, 6

Genomic Location:

Chr 11: 72653218-72687312

Description:

The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine n...

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The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GGGCGGR_SP1_Q6 ,  TGCTGAY_UNKNOWN ,  NCX_01

Cytogenetic Map:

11q13.4

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