QuickView for P4H-TM (gene)

Gene Symbol:

P4HTM Homo sapiens

Full name:

prolyl 4-hydroxylase, transmembrane

Synonyms:

EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4, transmembrane prolyl 4-hydroxylase, HIF-PH4, HIF-prolyl hydroxylase 4, HPH-4, P4H with transmembrane domain, Prolyl hydroxlase domain-containing 4, hypoxia-inducible factor prolyl 4-hydroxylase, hypoxia-inducible factor prolyl hydroxylase 4, proline 4-hydroxylase, prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

Genomic Location:

Chr 3: 49002345-49019586

Description:

The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different iso...

View Full Description

The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MAZR_01 ,  AACTGGA_MIR145 ,  GGGAGGRR_MAZ_Q6 ,  TGCCTTA_MIR124A ,  CCCNNGGGAR_OLF1_01 ,  YGCGYRCGC_UNKNOWN

Cytogenetic Map:

3p21.31::3p21.3

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