QuickView for PAI-1 (gene)
- Gene Symbol:
- SERPINE1
Canis lupus familiaris - Full name:
- serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- Synonyms:
- PAI-1
- Genomic Location:
- Chr 6: 11725307-11730642
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
enzyme binding | signaling receptor binding | protein binding | protease binding
GO Biological Process
regulation of leukocyte chemotaxis | regulation of odontoblast differentiation | positive regulation of locomotion | positive regulation of cellular component organization | response to lipopolysaccharide | regulation of localization | regulation of programmed cell death | defense response to other organism | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | defense response | negative regulation of cell-matrix adhesion | positive regulation of cellular component movement | defense response to Gram-negative bacterium | negative regulation of proteolysis | blood vessel morphogenesis | cellular process | regulation of cell motility | odontogenesis | negative regulation of smooth muscle cell migration | negative regulation of signaling | positive regulation of blood coagulation | regulation of chemotaxis | negative regulation of apoptotic process | negative regulation of smooth muscle cell-matrix adhesion | regulation of proteolysis | regulation of monocyte chemotaxis | negative regulation of cell migration | negative regulation of cellular metabolic process | regulation of cell differentiation | negative regulation of apoptotic signaling pathway | negative regulation of vascular wound healing | negative regulation of cell motility | negative regulation of wound healing | regulation of angiogenesis | positive regulation of interleukin-8 production | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | cellular response to molecule of bacterial origin | regulation of vasculature development | response to stimulus | negative regulation of epithelial cell apoptotic process | vasculature development | positive regulation of immune system process | regulation of plasminogen activation | negative regulation of cell adhesion | response to stress | negative regulation of angiogenesis | tube morphogenesis | regulation of epithelial cell differentiation | regulation of smooth muscle cell migration | cardiovascular system development | response to molecule of bacterial origin | negative regulation of metabolic process | regulation of wound healing | regulation of protein processing | regulation of cell adhesion | blood vessel development | response to external biotic stimulus | system development | positive regulation of response to wounding | regulation of signal transduction | positive regulation of monocyte chemotaxis | multicellular organism development | negative regulation of catalytic activity | regulation of peptidase activity | positive regulation of inflammatory response | regulation of catalytic activity | negative regulation of peptidase activity | regulation of receptor-mediated endocytosis | positive regulation of receptor-mediated endocytosis | regulation of gene expression | positive regulation of chemotaxis | regulation of extrinsic apoptotic signaling pathway | positive regulation of leukotriene production involved in inflammatory response | response to lipid | animal organ morphogenesis | regulation of blood coagulation | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cell-substrate adhesion | regulation of cellular component movement | regulation of endothelial cell apoptotic process | dentinogenesis | positive regulation of cell differentiation | negative regulation of extrinsic apoptotic signaling pathway | positive regulation of cell migration | regulation of cellular protein metabolic process | negative regulation of cell-substrate adhesion | angiogenesis | regulation of cell adhesion mediated by integrin | regulation of apoptotic signaling pathway | regulation of smooth muscle cell-matrix adhesion | regulation of epithelial cell apoptotic process | regulation of leukocyte migration | negative regulation of response to wounding | response to bacterium | regulation of cellular metabolic process | positive regulation of leukocyte chemotaxis | odontogenesis of dentin-containing tooth | negative regulation of protein processing | regulation of protein metabolic process | chronological cell aging | defense response to bacterium | regulation of locomotion | positive regulation of transport | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | cell aging | negative regulation of plasminogen activation | regulation of signaling receptor activity | response to organic substance | positive regulation of odontoblast differentiation | replicative senescence | positive regulation of mononuclear cell migration | anatomical structure development | regulation of body fluid levels | negative regulation of programmed cell death | positive regulation of coagulation | regulation of vesicle-mediated transport | negative regulation of gene expression | animal organ development | negative regulation of cellular protein metabolic process | negative regulation of cellular component movement | positive regulation of leukocyte migration | positive regulation of wound healing | positive regulation of cytokine production | anatomical structure formation involved in morphogenesis | negative regulation of protein metabolic process | regulation of response to wounding | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway via death domain receptors | regulation of endocytosis | regulation of fibrinolysis | regulation of cytokine production | anatomical structure morphogenesis | regulation of endopeptidase activity | response to biotic stimulus | regulation of developmental process | developmental process | positive regulation of epithelial cell differentiation | tube development | regulation of transport | negative regulation of cell adhesion mediated by integrin | negative regulation of vasculature development | regulation of vascular wound healing | negative regulation of hydrolase activity | negative regulation of fibrinolysis | cellular response to organic substance | regulation of cell death | positive regulation of cell motility | negative regulation of cell death | circulatory system development | regulation of inflammatory response | aging | negative regulation of locomotion | positive regulation of endocytosis | positive regulation of angiogenesis | regulation of cellular component organization | response to other organism | regulation of signaling | negative regulation of endopeptidase activity | negative regulation of endothelial cell apoptotic process | regulation of cell-matrix adhesion | cellular response to lipopolysaccharide | multicellular organismal process
GO Cellular Component
extracellular matrix | collagen-containing extracellular matrix | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space
