Correlation Engine 2.0
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QuickView for PALB2 (gene)


Gene Symbol:
PALB2 Homo sapiens Homo sapiens
Full name:
partner and localizer of BRCA2
Synonyms:
FANCN, PNCA3, partner and localizer of BRCA2, mutant partner and localizer of BRCA2
Genomic Location:
Chr 16: 23521984-23560179
Description:
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 16
16p12.2





GO Molecular Function

nucleic acid binding | DNA binding | organic cyclic compound binding | protein binding | heterocyclic compound binding

GO Biological Process

double-strand break repair | regulation of programmed cell death | negative regulation of cellular process | multicellular organism growth | pattern specification process | cellular process | developmental growth | mesoderm development | negative regulation of apoptotic process | inner cell mass cell proliferation | tissue development | regulation of cellular process | regulation of apoptotic process | organic cyclic compound metabolic process | epithelium development | cellular aromatic compound metabolic process | response to stimulus | response to stress | cellular nitrogen compound metabolic process | embryo development | DNA recombination | DNA repair | anterior/posterior pattern specification | system development | nitrogen compound metabolic process | double-strand break repair via homologous recombination | multicellular organism development | cellular response to DNA damage stimulus | cellular response to stress | animal organ morphogenesis | cell proliferation | chordate embryonic development | embryo development ending in birth or egg hatching | regionalization | DNA metabolic process | post-anal tail morphogenesis | anatomical structure development | metabolic process | negative regulation of programmed cell death | embryonic organ development | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | blastocyst development | anatomical structure formation involved in morphogenesis | somite development | anatomical structure morphogenesis | segmentation | recombinational repair | developmental process | blastocyst growth | heterocycle metabolic process | somitogenesis | in utero embryonic development | cellular metabolic process | regulation of cell death | negative regulation of cell death | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular