QuickView for PAN3;jsessionid=0E5DBFF4F6E4DD974C0414C201E206BF (gene)
- Gene Symbol:
- PAN3
Homo sapiens - Full name:
- PAN3 poly(A) specific ribonuclease subunit
- Synonyms:
- PAN2-PAN3 deadenylation complex subunit PAN3, PAB-dependent poly(A)-specific ribonuclease subunit PAN3, PAB-dependent poly(A)-specific ribonuclease subunit 3, PAB1P-dependent poly(A)-nuclease, PAB1P-dependent poly(A)-specific ribonuclease, PABP-dependent poly(A) nuclease 3, PABP1-dependent poly A-specific ribonuclease subunit PAN3, PAN deadenylation complex subunit 3, PAN3 poly(A) specific ribonuclease subunit homolog, poly(A)-nuclease deadenylation complex subunit 3
- Genomic Location:
- Chr 13: 27646417-27767472
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-129 , Predicted Gene Targets for miR-130 , Predicted Gene Targets for miR-133 , Predicted Gene Targets for miR-138 , Predicted Gene Targets for miR-186 , Predicted Gene Targets for miR-194 , Predicted Gene Targets for miR-199 , Predicted Gene Targets for miR-21 , Predicted Gene Targets for miR-26 , Predicted Gene Targets for miR-320
- Cytogenetic Map:
-
13q12.2
GO Molecular Function
nuclease activity | 3'-5'-exoribonuclease activity | cation binding | poly(A)-specific ribonuclease activity | nucleic acid binding | ribonucleotide binding | exoribonuclease activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ribonuclease activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | hydrolase activity, acting on ester bonds | exoribonuclease activity, producing 5'-phosphomonoesters | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | 3'-5' exonuclease activity | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | exonuclease activity | metal ion binding | heterocyclic compound binding | small molecule binding | RNA binding
GO Biological Process
RNA metabolic process | RNA processing | positive regulation of cellular component organization | nuclease activity | establishment of localization | 3'-5'-exoribonuclease activity | regulation of organelle organization | intracellular transport | cellular process | organic substance catabolic process | localization | protein transport | positive regulation of cytoplasmic mRNA processing body assembly | macromolecule localization | poly(A)-specific ribonuclease activity | establishment of localization in cell | regulation of cellular process | regulation of metabolic process | catabolic process | regulation of protein complex assembly | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | mRNA catabolic process | exoribonuclease activity | intracellular protein transport | deadenylation-dependent decapping of nuclear-transcribed mRNA | cellular localization | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | negative regulation of metabolic process | protein modification process | mRNA metabolic process | ribonuclease activity | nuclear-transcribed mRNA catabolic process | macromolecule modification | nucleobase-containing compound catabolic process | nitrogen compound metabolic process | positive regulation of organelle organization | phosphorus metabolic process | positive regulation of organelle assembly | regulation of gene expression | organic substance transport | RNA catabolic process | peptide transport | positive regulation of protein complex assembly | nuclear-transcribed mRNA poly(A) tail shortening | exoribonuclease activity, producing 5'-phosphomonoesters | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | aromatic compound catabolic process | protein metabolic process | regulation of cytoplasmic mRNA processing body assembly | cellular macromolecule catabolic process | metabolic process | 3'-5' exonuclease activity | cellular protein localization | amide transport | nucleobase-containing compound metabolic process | protein kinase activity | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of gene expression | RNA phosphodiester bond hydrolysis | gene expression | establishment of protein localization | RNA phosphodiester bond hydrolysis, exonucleolytic | protein localization | cellular protein metabolic process | cellular macromolecule localization | kinase activity | cellular protein modification process | exonuclease activity | heterocycle metabolic process | protein targeting | cellular metabolic process | mRNA processing | regulation of organelle assembly | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | regulation of cellular component organization | macromolecule metabolic process
GO Cellular Component
cell | ribonucleoprotein granule | cytoplasm | intracellular organelle | P-body | protein-containing complex | ribonucleoprotein complex | organelle | cytoplasmic ribonucleoprotein granule | cytosol | intracellular | PAN complex
